Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 6/20 | 0.54 |
| ▸ | GALR2 | O43603 | 9/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | JAK2 | O60674 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | GALR1 | P47211 | 1/20 | 0.48 |
| ▸ | SYK | P43405 | 1/20 | 0.47 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10143551 | 0.87 | GALR2 (0.67) | MAPTGALR2HTTMEN1MAPK1 | |
| SCHEMBL10143394 | 0.87 | GALR2 (0.67) | MAPTGALR2HTTMEN1MAPK1 | |
| SCHEMBL10143736 | 0.84 | GALR2 (0.53) | KDM4EMAPTGALR2MEN1MAPK1 | |
| SCHEMBL10143621 | 0.78 | GALR2 (0.80) | MAPTGALR2GALR1 | |
| SCHEMBL655538 | 0.77 | SYK (0.68) | KDM4ENFKB1MAPTHTTNPC1 | |
| SCHEMBL10143747 | 0.77 | GALR2 (0.84) | GALR2GALR1 | |
| SCHEMBL13763849 | 0.75 | GALR2 (0.50) | KDM4EMAPTGALR2MEN1MAPK1 | |
| SCHEMBL10144335 | 0.75 | GALR2 (0.71) | MAPTGALR2HTTMAPK1TDP1 | |
| SCHEMBL21313483 | 0.75 | MAPT (0.50) | MAPTMEN1MAPK1KMT2ASMN1; SMN2 | |
| SCHEMBL10143570 | 0.74 | GALR2 (0.53) | MAPTGALR2MEN1MAPK1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012009258-A2 | PEPTIDOMIMETIC GALANIN RECEPTOR MODULATORS | ROBERTS EDWARD (US) | 2012-01-19 | — | — | WO | disclosed |