Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 11/20 | 0.76 |
| ▸ | MTOR | P42345 | 10/20 | 0.76 |
| ▸ | SLC2A1 | P11166 | 2/20 | 0.58 |
| ▸ | SLC2A2 | P11168 | 2/20 | 0.58 |
| ▸ | SLC2A3 | P11169 | 2/20 | 0.58 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.52 |
| ▸ | PIK3C2B | O00750 | 1/20 | 0.52 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.52 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.50 |
| ▸ | CFTR | P13569 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10143802 | 0.90 | PIK3CA (0.60) | PIK3CAMTORSLC2A1SLC2A2SLC2A3 | |
| SCHEMBL3986325 | 0.86 | MTOR (1.00) | PIK3CAMTORALDH1A1HPGDHSD17B10 | |
| SCHEMBL4996109 | 0.84 | MTOR (0.82) | PIK3CAMTOR | |
| SCHEMBL10143801 | 0.83 | MERTK (0.68) | PIK3CAMTORSLC2A1SLC2A2SLC2A3 | |
| SCHEMBL4988955 | 0.82 | PIK3CA (1.00) | PIK3CAMTORALDH1A1HPGDHSD17B10 | |
| SCHEMBL4996533 | 0.81 | PIK3CA (0.86) | PIK3CAMTOR | |
| SCHEMBL3918530 | 0.81 | PIK3CA (1.00) | PIK3CAMTORALDH1A1HPGDHSD17B10 | |
| SCHEMBL4992629 | 0.80 | PIK3CA (0.83) | PIK3CAMTORPIK3CDPIK3CB | |
| SCHEMBL4991670 | 0.80 | PIK3CA (0.78) | PIK3CAMTORPIK3CD | |
| SCHEMBL3992571 | 0.79 | MTOR (0.75) | PIK3CAMTORALDH1A1HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012009258-A2 | PEPTIDOMIMETIC GALANIN RECEPTOR MODULATORS | ROBERTS EDWARD (US) | 2012-01-19 | — | — | WO | disclosed |