Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 8/20 | 0.60 |
| ▸ | MTOR | P42345 | 8/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.60 |
| ▸ | MAPT | P10636 | 3/20 | 0.60 |
| ▸ | RAB9A | P51151 | 3/20 | 0.60 |
| ▸ | HPGD | P15428 | 3/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.60 |
| ▸ | LMNA | P02545 | 2/20 | 0.60 |
| ▸ | TP53 | P04637 | 2/20 | 0.60 |
| ▸ | HTT | P42858 | 2/20 | 0.60 |
| ▸ | MITF | O75030 | 1/20 | 0.60 |
| ▸ | PKM | P14618 | 1/20 | 0.60 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.60 |
| ▸ | SLC2A1 | P11166 | 4/20 | 0.57 |
| ▸ | SLC2A2 | P11168 | 4/20 | 0.57 |
| ▸ | SLC2A3 | P11169 | 4/20 | 0.57 |
| ▸ | NPC1 | O15118 | 2/20 | 0.54 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10143799 | 0.90 | PIK3CA (0.76) | PIK3CAMTORALDH1A1HPGDLMNA | |
| SCHEMBL10143800 | 0.82 | MAPT (0.67) | PIK3CAMTORALDH1A1MAPTRAB9A | |
| SCHEMBL3986325 | 0.75 | MTOR (1.00) | PIK3CAMTORALDH1A1HPGDLMNA | |
| SCHEMBL4996109 | 0.74 | MTOR (0.82) | PIK3CAMTOR | |
| SCHEMBL10143801 | 0.73 | MERTK (0.68) | PIK3CAMTORALDH1A1MAPTRAB9A | |
| SCHEMBL4988955 | 0.71 | PIK3CA (1.00) | PIK3CAMTORALDH1A1HPGD | |
| SCHEMBL3918530 | 0.71 | PIK3CA (1.00) | PIK3CAMTORALDH1A1HPGDTP53 | |
| SCHEMBL4996533 | 0.71 | PIK3CA (0.86) | PIK3CAMTOR | |
| SCHEMBL21568696 | 0.70 | MAPT (1.00) | ALDH1A1MAPTRAB9AHPGDSMN1; SMN2 | |
| SCHEMBL29618261 | 0.70 | MAPT (1.00) | ALDH1A1MAPTRAB9AHPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012009258-A2 | PEPTIDOMIMETIC GALANIN RECEPTOR MODULATORS | ROBERTS EDWARD (US) | 2012-01-19 | — | — | WO | disclosed |