Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MERTK | Q12866 | 1/20 | 0.68 |
| ▸ | PIK3CA | P42336 | 9/20 | 0.59 |
| ▸ | MTOR | P42345 | 9/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.55 |
| ▸ | SLC2A2 | P11168 | 1/20 | 0.55 |
| ▸ | SLC2A3 | P11169 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 5/20 | 0.54 |
| ▸ | HPGD | P15428 | 5/20 | 0.54 |
| ▸ | HTT | P42858 | 4/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10143800 | 0.90 | MAPT (0.67) | MERTKPIK3CAMTORSMN1; SMN2NPC1 | |
| SCHEMBL10143799 | 0.83 | PIK3CA (0.76) | PIK3CAMTORSLC2A1SLC2A2SLC2A3 | |
| SCHEMBL1355170 | 0.78 | EIF2AK4 (0.61) | MERTKSMN1; SMN2NPC1RAB9AKMT2A | |
| SCHEMBL4992754 | 0.74 | PIK3CA (0.65) | PIK3CAMTORSMN1; SMN2NPC1RAB9A | |
| SCHEMBL29345032 | 0.74 | MEN1 (0.85) | MERTKSMN1; SMN2KMT2AMEN1LMNA | |
| SCHEMBL4996109 | 0.74 | MTOR (0.82) | PIK3CAMTOR | |
| SCHEMBL1355852 | 0.73 | FGFR4 (0.63) | SMN1; SMN2NPC1RAB9ASLC2A1 | |
| SCHEMBL10143802 | 0.73 | PIK3CA (0.60) | PIK3CAMTORSMN1; SMN2NPC1RAB9A | |
| SCHEMBL23187519 | 0.73 | MERTK (0.65) | MERTKSMN1; SMN2NPC1RAB9AKMT2A | |
| SCHEMBL427181 | 0.73 | MAPT (0.57) | MERTKSMN1; SMN2NPC1RAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3800188-A1 | SUBSTITUTED PYRAZOLOPYRIMIDINES AS IRAK4 INHIBITORS | Bayer AG (DE) | 2021-04-07 | — | — | EP | disclosed |
| WO-2012009258-A2 | PEPTIDOMIMETIC GALANIN RECEPTOR MODULATORS | ROBERTS EDWARD (US) | 2012-01-19 | — | — | WO | disclosed |