Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.67 |
| ▸ | LMNA | P02545 | 6/20 | 0.67 |
| ▸ | HTT | P42858 | 5/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.67 |
| ▸ | HPGD | P15428 | 4/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.67 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.67 |
| ▸ | MEN1 | O00255 | 3/20 | 0.67 |
| ▸ | RECQL | P46063 | 2/20 | 0.67 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.67 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.67 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.67 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.67 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.67 |
| ▸ | POLB | P06746 | 3/20 | 0.64 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.64 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.64 |
| ▸ | RAB9A | P51151 | 3/20 | 0.57 |
| ▸ | TP53 | P04637 | 2/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10143801 | 0.90 | MERTK (0.68) | MAPTLMNAHTTALDH1A1KMT2A | |
| SCHEMBL10143802 | 0.82 | PIK3CA (0.60) | MAPTLMNAHTTALDH1A1HPGD | |
| SCHEMBL1355752 | 0.76 | EIF2AK4 (0.62) | MAPTLMNAHTTALDH1A1KMT2A | |
| SCHEMBL16244524 | 0.73 | HTR2C (0.64) | ALDH1A1KMT2ASMN1; SMN2MEN1POLB | |
| SCHEMBL10143799 | 0.73 | PIK3CA (0.76) | LMNAHTTALDH1A1HPGDSLC2A1 | |
| SCHEMBL15452542 | 0.71 | HTR2C (0.67) | MAPTALDH1A1KMT2ANPSR1MEN1 | |
| SCHEMBL8891812 | 0.71 | MAPT (0.72) | MAPTLMNAHTTALDH1A1KMT2A | |
| SCHEMBL14503015 | 0.70 | MEN1 (0.75) | MAPTLMNAHTTALDH1A1KMT2A | |
| SCHEMBL1353701 | 0.69 | EIF2AK4 (0.60) | — | |
| SCHEMBL13759183 | 0.69 | LMNA (0.52) | MAPTLMNAHTTALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012009258-A2 | PEPTIDOMIMETIC GALANIN RECEPTOR MODULATORS | ROBERTS EDWARD (US) | 2012-01-19 | — | — | WO | disclosed |