Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 10/20 | 1.00 |
| ▸ | NPC1 | O15118 | 6/20 | 1.00 |
| ▸ | RAB9A | P51151 | 5/20 | 1.00 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 1.00 |
| ▸ | CASP3 | P42574 | 1/20 | 1.00 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 1.00 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 1.00 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 1.00 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.77 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.77 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.77 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.77 |
| ▸ | MAPT | P10636 | 5/20 | 0.74 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.74 |
| ▸ | POLB | P06746 | 3/20 | 0.74 |
| ▸ | LMNA | P02545 | 2/20 | 0.74 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.74 |
| ▸ | MEN1 | O00255 | 2/20 | 0.74 |
| ▸ | GAA | P10253 | 3/20 | 0.67 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13171361 | 0.85 | NPC1 (0.78) | L3MBTL1NPC1RAB9ASMN1; SMN2CASP3 | |
| SCHEMBL7037329 | 0.78 | KMT2A (0.67) | L3MBTL1NPC1RAB9ASMN1; SMN2CASP3 | |
| SCHEMBL23094253 | 0.78 | L3MBTL1 (1.00) | L3MBTL1NPC1RAB9ASMN1; SMN2CASP3 | |
| SCHEMBL18133382 | 0.76 | MAPT (0.71) | L3MBTL1NPC1RAB9ASMN1; SMN2CASP3 | |
| SCHEMBL4589468 | 0.72 | NPC1 (0.61) | L3MBTL1NPC1RAB9ASMN1; SMN2CASP3 | |
| SCHEMBL28670281 | 0.72 | NPC1 (0.59) | L3MBTL1NPC1RAB9ASMN1; SMN2CASP3 | |
| SCHEMBL236205 | 0.71 | HPGD (0.56) | L3MBTL1NPC1RAB9ASMN1; SMN2CASP3 | |
| SCHEMBL14669481 | 0.71 | L3MBTL1 (0.73) | L3MBTL1NPC1RAB9ASMN1; SMN2CASP3 | |
| Hydrochloric Acid SCHEMBL27610313 | 0.70 | HPGD (0.54) | L3MBTL1NPC1RAB9ASMN1; SMN2CASP3 | |
| SCHEMBL5350551 | 0.69 | RAB9A (0.76) | NPC1RAB9ASMN1; SMN2CYP2C9ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120100609-A1 | N-LINKED GLYCAN BIOSYNTHESIS MODULATORS | BIOMARIN PHARMACEUTICAL INC. | 2012-04-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120100609-A1 | N-LINKED GLYCAN BIOSYNTHESIS MODULATORS | ENGASE, GALNT1, GALNT13 | L3MBTL1 1767/4885NPC1 764/4885RAB9A 3256/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.