Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.67 |
| ▸ | TSHR | P16473 | 4/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.65 |
| ▸ | MEN1 | O00255 | 4/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.62 |
| ▸ | LMNA | P02545 | 1/20 | 0.62 |
| ▸ | MAPT | P10636 | 1/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | ATM | Q13315 | 2/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
| ▸ | HSD11B1 | P28845 | 3/20 | 0.56 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.56 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.55 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.55 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | USP2 | O75604 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29060798 | 0.87 | TSHR (0.61) | POLBKDM4ETSHRSMN1; SMN2MEN1 | |
| SCHEMBL18711911 | 0.82 | KMT2A (0.67) | POLBTSHRSMN1; SMN2MEN1KMT2A | |
| SCHEMBL18701976 | 0.80 | HSD17B10 (0.57) | POLBTSHRSMN1; SMN2MEN1KMT2A | |
| SCHEMBL494192 | 0.80 | KDM4E (0.74) | POLBKDM4ETSHRSMN1; SMN2MEN1 | |
| SCHEMBL493045 | 0.78 | POLB (0.72) | POLBKDM4ETSHRMEN1KMT2A | |
| SCHEMBL10763658 | 0.78 | MEP1B (0.55) | POLBTSHRSMN1; SMN2MEN1KMT2A | |
| SCHEMBL17953068 | 0.78 | KMT2A (0.58) | POLBTSHRSMN1; SMN2MEN1KMT2A | |
| SCHEMBL22081156 | 0.78 | MEN1 (0.69) | POLBTSHRSMN1; SMN2MEN1KMT2A | |
| SCHEMBL6209362 | 0.78 | MEP1B (0.54) | POLBTSHRSMN1; SMN2MEN1KMT2A | |
| SCHEMBL1946969 | 0.77 | L3MBTL1 (0.68) | POLBTSHRSMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120100609-A1 | N-LINKED GLYCAN BIOSYNTHESIS MODULATORS | BIOMARIN PHARMACEUTICAL INC. | 2012-04-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120100609-A1 | N-LINKED GLYCAN BIOSYNTHESIS MODULATORS | ENGASE, GALNT1, GALNT13 | POLB 2362/4885KDM4E 3708/4885TSHR 2802/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.