Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.38 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.38 |
| ▸ | TLR2 | O60603 | 1/20 | 0.38 |
| ▸ | TLR1 | Q15399 | 1/20 | 0.38 |
| ▸ | PRCP | P42785 | 1/20 | 0.37 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.37 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.36 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MMP1 | P03956 | 1/20 | 0.35 |
| ▸ | MMP3 | P08254 | 1/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.35 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10144420 | 0.89 | NTMT1 (0.45) | ITGB1ITGA4TLR2PRCPNPSR1 | |
| SCHEMBL10143583 | 0.89 | TLR2 (0.38) | CA1CA2TLR2TLR1MDM2 | |
| SCHEMBL10144432 | 0.88 | CA1 (0.45) | CA1CA2TLR2TLR1MDM2 | |
| SCHEMBL10143496 | 0.85 | CA1 (0.42) | CA1CA2TLR2TLR1MDM2 | |
| SCHEMBL10144130 | 0.84 | CA1 (0.39) | CA1CA2TLR2TLR1MDM2 | |
| SCHEMBL10144194 | 0.84 | MDM2 (0.39) | CA1CA2TLR2TLR1MDM2 | |
| SCHEMBL10143500 | 0.83 | SIRT5 (0.42) | CA1CA2TLR2TLR1MDM2 | |
| SCHEMBL10143509 | 0.83 | CACNA1B (0.39) | CA1CA2TLR2TLR1MDM2 | |
| SCHEMBL10144210 | 0.82 | MDM2 (0.40) | CA1CA2TLR2TLR1MDM2 | |
| SCHEMBL30313463 | 0.82 | TLR2 (0.47) | TLR2TLR1PRCPMDM2ITGB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012009258-A2 | PEPTIDOMIMETIC GALANIN RECEPTOR MODULATORS | ROBERTS EDWARD (US) | 2012-01-19 | — | — | WO | disclosed |