Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR2 | O60603 | 2/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 6/20 | 0.35 |
| ▸ | HDAC11 | Q96DB2 | 6/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 6/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 5/20 | 0.35 |
| ▸ | HDAC10 | Q969S8 | 5/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 5/20 | 0.35 |
| ▸ | NTMT1 | Q9BV86 | 2/20 | 0.35 |
| ▸ | PLG | P00747 | 2/20 | 0.35 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.35 |
| ▸ | FDFT1 | P37268 | 1/20 | 0.33 |
| ▸ | F11 | P03951 | 1/20 | 0.33 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.32 |
| ▸ | EP300 | Q09472 | 1/20 | 0.32 |
| ▸ | MEF2D | Q14814 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10143583 | 0.90 | TLR2 (0.38) | TLR2HDAC3HDAC11HDAC6HDAC1 | |
| SCHEMBL10144420 | 0.87 | NTMT1 (0.45) | TLR2HDAC3HDAC11HDAC6HDAC1 | |
| SCHEMBL10144446 | 0.83 | TLR2 (0.43) | TLR2PLGKLKB1TPSAB1HDAC4 | |
| SCHEMBL10144324 | 0.81 | TLR2 (0.44) | TLR2TPSAB1HDAC4EP300MEF2D | |
| SCHEMBL10143499 | 0.80 | TLR2 (0.45) | TLR2TPSAB1HDAC4EP300MEF2D | |
| SCHEMBL10143518 | 0.80 | TLR2 (0.43) | TLR2TPSAB1HDAC4EP300MEF2D | |
| SCHEMBL10143502 | 0.79 | TLR2 (0.45) | TLR2TPSAB1HDAC4EP300MEF2D | |
| SCHEMBL10144422 | 0.77 | CA1 (0.39) | TLR2HDAC3HDAC11HDAC6HDAC1 | |
| SCHEMBL10143401 | 0.76 | TLR2 (0.46) | TLR2HDAC3HDAC11HDAC6HDAC1 | |
| SCHEMBL10143497 | 0.76 | TLR2 (0.42) | TLR2HDAC1HDAC2TPSAB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012009258-A2 | PEPTIDOMIMETIC GALANIN RECEPTOR MODULATORS | ROBERTS EDWARD (US) | 2012-01-19 | — | — | WO | disclosed |