Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.74 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.74 |
| ▸ | LMNA | P02545 | 3/20 | 0.65 |
| ▸ | MRGPRX4 | Q96LA9 | 4/20 | 0.57 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.52 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.51 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6000185 | 0.82 | LOXL2 (0.70) | ALDH1A1NPSR1MRGPRX4MAPTLOXL2 | |
| SCHEMBL6667451 | 0.78 | LOXL2 (0.64) | ALDH1A1LMNAMRGPRX4MAPTLOXL2 | |
| SCHEMBL28869399 | 0.76 | LOXL2 (0.62) | ALDH1A1NPSR1MRGPRX4MAPTLOXL2 | |
| SCHEMBL10235310 | 0.76 | MAPT (0.63) | ALDH1A1LMNAMRGPRX4MAPTLOXL2 | |
| SCHEMBL1544193 | 0.76 | LOXL2 (0.70) | ALDH1A1MRGPRX4MAPTLOXL2CYP4F2 | |
| SCHEMBL31276343 | 0.76 | LOXL2 (0.70) | ALDH1A1MRGPRX4MAPTLOXL2CYP4F2 | |
| SCHEMBL5277923 | 0.75 | CYP4F2 (0.68) | ALDH1A1NPSR1MRGPRX4MAPTLOXL2 | |
| SCHEMBL10144968 | 0.75 | LOXL2 (0.64) | ALDH1A1MRGPRX4MAPTLOXL2CYP4F2 | |
| SCHEMBL979564 | 0.74 | ALDH1A1 (0.58) | ALDH1A1NPSR1LMNAMRGPRX4MAPT | |
| SCHEMBL19764837 | 0.74 | LOXL2 (0.62) | ALDH1A1MRGPRX4MAPTLOXL2CYP4F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120100609-A1 | N-LINKED GLYCAN BIOSYNTHESIS MODULATORS | BIOMARIN PHARMACEUTICAL INC. | 2012-04-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120100609-A1 | N-LINKED GLYCAN BIOSYNTHESIS MODULATORS | ENGASE, GALNT1, GALNT13 | ALDH1A1 2125/4885NPSR1 2181/4885LMNA 4109/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.