Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.68 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.68 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.68 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.60 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.55 |
| ▸ | CFTR | P13569 | 5/20 | 0.53 |
| ▸ | MEN1 | O00255 | 4/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.53 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.53 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.53 |
| ▸ | DUSP22 | Q9NRW4 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.51 |
| ▸ | PSD | A5PKW4 | 1/20 | 0.50 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.49 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26485794 | 0.81 | MAPT (1.00) | MAPTMAPK1TDP1AMY1AMAP3K5 | |
| SCHEMBL26485784 | 0.81 | MAPT (1.00) | MAPTMAPK1TDP1AMY1AMAP3K5 | |
| SCHEMBL13236134 | 0.78 | HSPD1 (0.59) | MAPTMAPK1TDP1AMY1ACFTR | |
| SCHEMBL14788063 | 0.78 | HSPD1 (0.76) | MAPTMAPK1TDP1MAP3K5CFTR | |
| SCHEMBL6720202 | 0.77 | MEN1 (0.65) | MAPTMAPK1TDP1AMY1ACFTR | |
| SCHEMBL2184682 | 0.75 | HSPD1 (0.62) | MAPTMAPK1TDP1CFTRMEN1 | |
| SCHEMBL2184686 | 0.75 | HSPD1 (0.62) | MAPTMAPK1TDP1CFTRMEN1 | |
| SCHEMBL12637256 | 0.73 | CFTR (0.78) | MAPTMAPK1TDP1CFTRMEN1 | |
| SCHEMBL13401425 | 0.73 | DUSP22 (0.57) | MAPTMAPK1TDP1AMY1AMEN1 | |
| SCHEMBL12637132 | 0.73 | CFTR (0.74) | MAPTAMY1ACFTRMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120100609-A1 | N-LINKED GLYCAN BIOSYNTHESIS MODULATORS | BIOMARIN PHARMACEUTICAL INC. | 2012-04-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120100609-A1 | N-LINKED GLYCAN BIOSYNTHESIS MODULATORS | ENGASE, GALNT1, GALNT13 | MAPT 2982/4885MAPK1 3681/4885TDP1 3072/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.