Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DUSP22 | Q9NRW4 | 1/20 | 0.57 |
| ▸ | PSD | A5PKW4 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 9/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.55 |
| ▸ | MAPT | P10636 | 4/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 5/20 | 0.52 |
| ▸ | USP2 | O75604 | 1/20 | 0.52 |
| ▸ | CASP6 | P55212 | 1/20 | 0.52 |
| ▸ | BLM | P54132 | 2/20 | 0.51 |
| ▸ | PLG | P00747 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9120921 | 0.82 | DUSP22 (0.64) | DUSP22PSDMEN1KMT2AALDH1A1 | |
| SCHEMBL3904145 | 0.80 | PTPN12 (0.60) | DUSP22MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL3904147 | 0.80 | PTPN12 (0.60) | DUSP22MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL9618990 | 0.80 | MEN1 (0.56) | DUSP22PSDMEN1KMT2AALDH1A1 | |
| SCHEMBL9618989 | 0.80 | MEN1 (0.56) | DUSP22PSDMEN1KMT2AALDH1A1 | |
| SCHEMBL5993646 | 0.75 | PSD (0.77) | DUSP22PSDMEN1KMT2AALDH1A1 | |
| SCHEMBL3890702 | 0.74 | PTPN12 (0.66) | DUSP22MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL3890707 | 0.74 | PTPN12 (0.66) | DUSP22MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL10144740 | 0.73 | MAPT (0.68) | DUSP22PSDMEN1KMT2AMAPT | |
| SCHEMBL17762590 | 0.72 | DUSP22 (1.00) | DUSP22MEN1KMT2AALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100093611-A1 | COMPOUNDS AND METHODS FOR TREATING OR PREVENTING AUTOIMMUNE DISEASES | AVALON PHARMACEUTICALS, INC. | 2010-04-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100093611-A1 | COMPOUNDS AND METHODS FOR TREATING OR PREVENTING AUTOIMMUNE DISEASES | IKBKB, IKBKG, NFKBIA | DUSP22 728/4885PSD 4398/4885MEN1 3698/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.