Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.69 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.69 |
| ▸ | HTT | P42858 | 2/20 | 0.69 |
| ▸ | MAPT | P10636 | 4/20 | 0.66 |
| ▸ | ESR1 | P03372 | 1/20 | 0.66 |
| ▸ | GAA | P10253 | 1/20 | 0.66 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.64 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.64 |
| ▸ | PIK3C2A | O00443 | 1/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.61 |
| ▸ | MEN1 | O00255 | 4/20 | 0.61 |
| ▸ | CTDSP1 | Q9GZU7 | 2/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.61 |
| ▸ | BLM | P54132 | 1/20 | 0.61 |
| ▸ | TGM2 | P21980 | 1/20 | 0.60 |
| ▸ | TP53 | P04637 | 1/20 | 0.60 |
| ▸ | BRD3 | Q15059 | 2/20 | 0.58 |
| ▸ | RECQL | P46063 | 1/20 | 0.57 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3913381 | 0.81 | ALDH1A1 (0.71) | KDM4EALDH1A1NPSR1HTTMAPT | |
| SCHEMBL19079839 | 0.80 | KDM4E (0.73) | KDM4EALDH1A1NPSR1HTTMAPT | |
| SCHEMBL541068 | 0.79 | KMT2A (0.73) | KDM4EALDH1A1NPSR1HTTMAPT | |
| SCHEMBL21586309 | 0.77 | PIK3C2A (1.00) | KDM4EALDH1A1GAAPIK3C2AKMT2A | |
| SCHEMBL30003012 | 0.77 | PIK3C2A (1.00) | KDM4EALDH1A1GAAPIK3C2AKMT2A | |
| SCHEMBL15722389 | 0.77 | KDM4E (0.73) | KDM4EALDH1A1NPSR1HTTMAPT | |
| SCHEMBL12857883 | 0.76 | KMT2A (0.74) | KDM4EALDH1A1NPSR1HTTMAPT | |
| SCHEMBL5805462 | 0.76 | KDM4E (0.71) | KDM4EALDH1A1NPSR1HTTMAPT | |
| SCHEMBL15506196 | 0.75 | KDM4E (0.68) | KDM4EALDH1A1NPSR1HTTMAPT | |
| SCHEMBL6037625 | 0.75 | TGM2 (1.00) | KDM4EALDH1A1NPSR1HTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120100609-A1 | N-LINKED GLYCAN BIOSYNTHESIS MODULATORS | BIOMARIN PHARMACEUTICAL INC. | 2012-04-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120100609-A1 | N-LINKED GLYCAN BIOSYNTHESIS MODULATORS | ENGASE, GALNT1, GALNT13 | KDM4E 3708/4885ALDH1A1 2125/4885NPSR1 2181/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.