Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FTO | Q9C0B1 | 2/20 | 0.56 |
| ▸ | SOS1 | Q07889 | 2/20 | 0.48 |
| ▸ | CYP1A1 | P04798 | 6/20 | 0.44 |
| ▸ | CYP1B1 | Q16678 | 6/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | GNG2 | P59768 | 1/20 | 0.40 |
| ▸ | GNB1 | P62873 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15139517 | 0.86 | SOS1 (0.66) | FTOSOS1CYP1A1CYP1B1CYP1A2 | |
| SCHEMBL10175853 | 0.85 | FTO (0.56) | FTOSOS1CYP1A1CYP1B1CYP1A2 | |
| SCHEMBL10145484 | 0.83 | FTO (0.48) | FTOSOS1CYP1A1CYP1B1CYP1A2 | |
| SCHEMBL10145497 | 0.81 | FTO (0.54) | FTOSOS1CYP1A1CYP1B1CYP1A2 | |
| SCHEMBL10145463 | 0.81 | SOS1 (0.72) | SOS1KDM4EPOLBGNG2GNB1 | |
| SCHEMBL12393718 | 0.76 | FTO (0.64) | FTOSOS1KDM4EPOLBGNG2 | |
| SCHEMBL2059938 | 0.75 | FTO (0.57) | FTOSOS1CYP1A1CYP1B1CYP1A2 | |
| SCHEMBL13678651 | 0.74 | FTO (0.77) | FTOSOS1CYP1B1CYP1A2KDM4E | |
| SCHEMBL10145468 | 0.74 | FTO (0.48) | FTOSOS1CYP1A1CYP1B1CYP1A2 | |
| SCHEMBL14626814 | 0.72 | FTO (0.59) | FTOSOS1KDM4EPOLBGNG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8114904-B2 | Luminescence quenchers and fluorogenic probes for detection of reactive species | Versitech Limited & Morningside Ventures Limited (CN) | 2012-02-14 | — | — | US | disclosed |
| US-20090253118-A1 | LUMINESCENCE QUENCHERS AND FLUOROGENIC PROBES FOR DETECTION OF REACTIVE SPECIES | VERSITECH LIMITED (CN) | 2009-10-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090253118-A1 | LUMINESCENCE QUENCHERS AND FLUOROGENIC PROBES FOR DETECTION OF REACTIVE SPECIES | ROS1, LPO, HMOX1 | FTO 244/4885SOS1 1103/4885CYP1A1 346/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.