Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 2/20 | 0.37 |
| ▸ | HTR2A | P28223 | 2/20 | 0.33 |
| ▸ | HRH1 | P35367 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13971379 | 0.80 | ROCK1 (0.30) | ROCK1 | |
| SCHEMBL14410803 | 0.75 | NFKB1 (0.32) | — | |
| SCHEMBL19198235 | 0.73 | MEN1 (0.31) | — | |
| SCHEMBL23280225 | 0.72 | NISCH (0.32) | — | |
| SCHEMBL22386250 | 0.72 | — | — | |
| SCHEMBL20825081 | 0.72 | — | — | |
| SCHEMBL23332630 | 0.70 | — | — | |
| SCHEMBL20676308 | 0.69 | — | — | |
| SCHEMBL30374678 | 0.69 | NISCH (0.30) | — | |
| SCHEMBL8635094 | 0.69 | ALDH1A1 (0.32) | ROCK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2415765-A1 | PYRIMIDINE COMPOUND | Astellas Pharma Inc. (JP) | 2012-02-08 | — | — | EP | disclosed |