Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23280225 | 0.78 | NISCH (0.32) | RAB9A | |
| SCHEMBL14410803 | 0.77 | NFKB1 (0.32) | — | |
| SCHEMBL30374678 | 0.75 | NISCH (0.30) | — | |
| SCHEMBL10145891 | 0.73 | HTR2C (0.37) | — | |
| SCHEMBL19198114 | 0.72 | ALDH1A1 (0.31) | HPGD | |
| SCHEMBL13971379 | 0.71 | ROCK1 (0.30) | — | |
| SCHEMBL24080717 | 0.71 | MAPT (0.37) | MEN1NPC1MAPTHPGDRAB9A | |
| SCHEMBL12888028 | 0.71 | — | — | |
| SCHEMBL12707388 | 0.71 | ALDH1A1 (0.31) | — | |
| SCHEMBL18903983 | 0.71 | ALDH1A1 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170217996-A1 | Large-scale diastereoselective syntheses of cycloheptadienylsulfones and stereotetrads | PURDUE RESEARCH FOUNDATION (US) | 2017-08-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170217996-A1 | Large-scale diastereoselective syntheses of cycloheptadienylsulfones and stereotetrads | DHPS, STS, FDFT1 | MEN1 1421/4885NPC1 4766/4885MAPT 3476/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.