SCHEMBL10147534

SCHEMBL10147534

CC(C)(C)c1cc(-c2nnc(C(C)(C)SCC3CCOCC3)[nH]2)on1

nearest known ligand 0.34

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CNR2 P34972 4/20 0.34
CNR1 P21554 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL350081 0.79 CNR2 (0.42) CNR2CNR1
SCHEMBL10147517 0.79 CNR2 (0.35) CNR2
SCHEMBL10147797 0.77 CNR2 (0.35) CNR2CNR1
SCHEMBL10147513 0.76 CNR2 (0.35) CNR2CNR1
SCHEMBL10146092 0.75 ALDH1A1 (0.36)
SCHEMBL13618722 0.71 ALDH1A1 (0.34)
SCHEMBL1252399 0.71 CNR2 (0.38) CNR2CNR1
SCHEMBL10147799 0.70 KDM4E (0.32)
SCHEMBL10147511 0.69 MAPK14 (0.36)
SCHEMBL12747061 0.66 ALDH1A1 (0.36)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2418207-A1 Sulfone compounds which modulate the CB2 receptor Boehringer Ingelheim International GmbH (DE) 2012-02-15 EP disclosed