Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 11/20 | 0.35 |
| ▸ | CNR1 | P21554 | 5/20 | 0.32 |
| ▸ | IKBKE | Q14164 | 1/20 | 0.30 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10147513 | 0.81 | CNR2 (0.35) | CNR2CNR1 | |
| SCHEMBL351342 | 0.79 | CNR2 (0.46) | CNR2CNR1 | |
| SCHEMBL10147534 | 0.77 | CNR2 (0.34) | CNR2CNR1 | |
| SCHEMBL10147581 | 0.75 | CNR2 (0.34) | CNR2CNR1 | |
| SCHEMBL352505 | 0.75 | CNR2 (0.43) | CNR2CNR1IKBKETBK1 | |
| SCHEMBL10146116 | 0.74 | CYP1A2 (0.37) | CNR2 | |
| SCHEMBL1250804 | 0.72 | CNR2 (0.42) | CNR2CNR1 | |
| SCHEMBL13618545 | 0.70 | ALDH1A1 (0.32) | — | |
| SCHEMBL10147579 | 0.68 | NPC1 (0.33) | — | |
| SCHEMBL10147586 | 0.67 | CNR2 (0.35) | CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2418207-A1 | Sulfone compounds which modulate the CB2 receptor | Boehringer Ingelheim International GmbH (DE) | 2012-02-15 | — | — | EP | disclosed |