Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10146092 | 0.89 | ALDH1A1 (0.36) | ALDH1A1KDM4EMEN1HPGDKMT2A | |
| SCHEMBL12747061 | 0.78 | ALDH1A1 (0.36) | ALDH1A1KDM4EMEN1HPGDKMT2A | |
| SCHEMBL10147818 | 0.78 | ALDH1A1 (0.36) | ALDH1A1KDM4EMEN1HPGDKMT2A | |
| SCHEMBL10147511 | 0.74 | MAPK14 (0.36) | MEN1HPGDKMT2A | |
| SCHEMBL351776 | 0.73 | CNR2 (0.39) | MEN1KMT2A | |
| SCHEMBL350956 | 0.73 | PTGS2 (0.34) | ALDH1A1HPGDHSD17B10 | |
| SCHEMBL10147554 | 0.72 | LMNA (0.32) | — | |
| SCHEMBL10147534 | 0.71 | CNR2 (0.34) | — | |
| SCHEMBL13618729 | 0.70 | — | — | |
| SCHEMBL350081 | 0.70 | CNR2 (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009140089-A2 | SULFONE COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2009-11-19 | — | — | WO | disclosed |