SCHEMBL1014778

SCHEMBL1014778

C=C(C)OC(=O)/C=C\C(=O)O

nearest known ligand 0.52

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
HCAR2 Q8TDS4 11/20 0.52
TDP1 Q9NUW8 3/20 0.46
HSD17B10 Q99714 3/20 0.46
TSHR P16473 4/20 0.43
TP53 P04637 1/20 0.43
EGLN1 Q9GZT9 1/20 0.43
EGLN3 Q9H6Z9 1/20 0.43
ALDH1A1 P00352 5/20 0.41
KDM4E B2RXH2 1/20 0.41
MAPT P10636 1/20 0.41
ALOX15 P16050 2/20 0.38
RECQL P46063 2/20 0.38
KEAP1 Q14145 1/20 0.36
NFE2L2 Q16236 1/20 0.36
GAA P10253 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4168638 1.00 HCAR2 (0.52) HCAR2TDP1HSD17B10TSHRTP53
SCHEMBL5455988 0.90 TDP1 (0.55) HCAR2TDP1HSD17B10TSHRALDH1A1
SCHEMBL8943894 0.90 TDP1 (0.55) HCAR2TDP1HSD17B10TSHRALDH1A1
SCHEMBL5456001 0.90 TDP1 (0.55) HCAR2TDP1HSD17B10TSHRALDH1A1
Ether SCHEMBL19924309 0.88 HCAR2 (0.52) HCAR2TDP1HSD17B10TSHRTP53
Fumaric Acid SCHEMBL3701419 0.87 HSD17B10 (0.52) HCAR2TDP1HSD17B10TSHRTP53
Maleic Acid SCHEMBL251369 0.87 HSD17B10 (0.52) HCAR2TDP1HSD17B10TSHRTP53
Maleic Acid SCHEMBL4507841 0.85 HSD17B10 (0.50) HCAR2TDP1HSD17B10TSHRTP53
Fumaric Acid SCHEMBL9248586 0.85 HSD17B10 (0.50) HCAR2TDP1HSD17B10TSHRTP53
Monomethyl Fumarate SCHEMBL7123923 0.85 HCAR2 (0.71) HCAR2TDP1HSD17B10TSHRTP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4368686-B1 LUBRICITY IMPROVER COMPOSITION FOR FUEL OIL AND USE THEREOF CHINA PETROLEUM & CHEM CORP (CN) 2026-05-27 EP disclosed
US-12365847-B2 Lubricity improver composition for fuel oil and use thereof CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2025-07-22 US disclosed
US-20240368490-A1 LUBRICITY IMPROVER COMPOSITION FOR FUEL OIL AND USE THEREOF Sinopec Research Institute of Petroleum Processing Co., Ltd. (CN) 2024-11-07 US disclosed
EP-4368686-A1 LUBRICITY IMPROVER COMPOSITION FOR FUEL OIL AND USE THEREOF China Petroleum & Chemical Corporation (CN) 2024-05-15 EP disclosed
CN-115537242-A Diesel antiwear agent composition, preparation method thereof and diesel composition 中国石油化工股份有限公司 2022-12-30 CN disclosed
CN-115141663-A Additive for improving lubricating performance of gasoline and gasoline composition 中国石油化工股份有限公司 2022-10-04 CN disclosed
CN-113462443-A Diesel antiwear agent composition, preparation method thereof and diesel composition 中国石油化工股份有限公司 2021-10-01 CN disclosed
EP-2271309-A1 SHAMPOO WITH FRUIT JUICE AND/OR VEGETABLE JUICE Henkel AG & Co. KGaA (DE) 2011-01-12 EP disclosed
WO-2009135699-A1 SHAMPOO WITH FRUIT JUICE AND/OR VEGETABLE JUICE HENKEL AG & CO. KGAA (DE) 2009-11-12 WO disclosed
US-20090247680-A1 ADHESION PROMOTING ADDITIVE AVERY DENNISON CORPORATION (US) 2009-10-01 US disclosed
US-5750263-A Low fogging rubbery polymer THE GOODYEAR TIRE & RUBBER COMPANY (US) 1998-05-12 US disclosed
EP-0799856-A2 Composition having low compression set THE GOODYEAR TIRE & RUBBER COMPANY (US) 1997-10-08 EP disclosed
US-5674933-A POLYMER FROM BUTYL ACRYLATE, STYRENE, ACRYLONITRILE, AT LEAST ONE OF METHYL METHACRYLATE, METHYL ACRYLATE, ETHYL METHACYLATE, OR ETHYL ACRYLATE, AND CROSSLINKING AGENT THE GOODYEAR TIRE & RUBBER COMPANY (US) 1997-10-07 US disclosed
EP-0780409-A2 Low fogging rubbery polymer THE GOODYEAR TIRE & RUBBER COMPANY (US) 1997-06-25 EP disclosed
EP-0550486-A1 PROCESS FOR PRODUCING CONCENTRATED AQUEOUS SOLUTIONS OF ANIONIC AZO DYES. HOECHST AG (DE) 1993-07-14 EP disclosed
WO-1992006140-A1 PROCESS FOR PRODUCING CONCENTRATED AQUEOUS SOLUTIONS OF ANIONIC AZO DYES HOECHST AKTIENGESELLSCHAFT (DE) 1992-04-16 WO disclosed
EP-0140530-B1 LATENTLY-CURABLE ORGANOSILICONE RELEASE COATING COMPOSITION MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1989-03-08 EP disclosed
US-4533575-A ETHYLENICALLY UNSATURATED POLYSILOXANE AND POLYHYDROSILOXANE MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1985-08-06 US disclosed
EP-0140530-A1 Latently-curable organosilicone release coating composition MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1985-05-08 EP disclosed
US-4504645-A GELATION INHIBITION USING A MONOESTER OR -AMIDE OF AN UNSATURATED DICARBOXYLIC ACID; SHELF LIFE; HEAT CURING MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1985-03-12 US disclosed