Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | HCAR2 | Q8TDS4 | 5/20 | 0.43 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.43 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5455988 | 1.00 | TDP1 (0.55) | TDP1HSD17B10HCAR2KEAP1NFE2L2 | |
| SCHEMBL8943894 | 1.00 | TDP1 (0.55) | TDP1HSD17B10HCAR2KEAP1NFE2L2 | |
| SCHEMBL1014778 | 0.90 | HCAR2 (0.52) | TDP1HSD17B10HCAR2KEAP1NFE2L2 | |
| SCHEMBL4168638 | 0.90 | HCAR2 (0.52) | TDP1HSD17B10HCAR2KEAP1NFE2L2 | |
| SCHEMBL14937356 | 0.87 | — | — | |
| SCHEMBL14937359 | 0.87 | — | — | |
| SCHEMBL864808 | 0.80 | — | — | |
| Ether SCHEMBL19924309 | 0.79 | HCAR2 (0.52) | TDP1HSD17B10HCAR2ALDH1A1TSHR | |
| SCHEMBL8610770 | 0.78 | ALDH1A1 (0.48) | TDP1HSD17B10HCAR2KEAP1NFE2L2 | |
| SCHEMBL8595889 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070293595-A1 | INITIATION OF POLYMERIZATION BY HYDROGEN ATOM DONATION | E. I. DUPONT DE NEMOURS AND COMPANY (US) | 2007-12-20 | — | — | US | disclosed |
| US-20060111535-A1 | Processes including initiation of polymerization by hydrogen atom donation | GRIDNEV ALEXEI A | 2006-05-25 | — | — | US | disclosed |
| US-7022792-B2 | Initiation of polymerization by hydrogen atom donation | E. I. DUPONT DE NEMOURS AND COMPANY (US) | 2006-04-04 | — | — | US | disclosed |
| WO-2005090414-A1 | INITIATION OF POLYMERIZATION BY HYDROGEN ATOM DONATION | E.I. DUPONT DE NEMOURS AND COMPANY (US) | 2005-09-29 | — | — | WO | disclosed |
| US-20050209418-A1 | Initiation of polymerization by hydrogen atom donation | E. I. DU PONT DE NEMOURS AND COMPANY | 2005-09-22 | — | — | US | disclosed |
| US-5576054-A | ULTRAVIOLET RESISTANT OPAQUE GLASS COATING | GENERAL ELECTRIC COMPANY (US) | 1996-11-19 | — | — | US | disclosed |
| EP-0234720-B1 | SILICONE RUBBER COMPOSITIONS | GENERAL ELECTRIC COMPANY (US) | 1991-09-18 | — | — | EP | disclosed |
| EP-0234720-A1 | Silicone rubber compositions | GENERAL ELECTRIC COMPANY (US) | 1987-09-02 | — | — | EP | disclosed |
| US-3941741-A | POLYSILOXANE | GENERAL ELECTRIC COMPANY (US) | 1976-03-02 | — | — | US | disclosed |