SCHEMBL1014782

SCHEMBL1014782

O=C1OC(=O)C(O)SC1O

nearest known ligand 0.31

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.31
GMNN O75496 1/20 0.31
PPM1B O75688 1/20 0.31
LMNA P02545 1/20 0.31
PPP1CC P36873 1/20 0.31
TFPI2 P48307 1/20 0.31
RAB9A P51151 1/20 0.31
PPP5C P53041 1/20 0.31
PPP1CA P62136 1/20 0.31
PMP22 Q01453 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
TP53 P04637 1/20 0.31
CYP2D6 P10635 1/20 0.31
NFKB1 P19838 1/20 0.31
THPO P40225 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6045969 0.81 KDM4E (0.31) KDM4EGMNNPPM1BLMNAPPP1CC
SCHEMBL2470524 0.69
SCHEMBL375777 0.69
SCHEMBL4165018 0.65 LMNA (0.42) KDM4EGMNNPPM1BLMNAPPP1CC
SCHEMBL14187990 0.60 KDM4E (0.38) KDM4EGMNNPPM1BLMNAPPP1CC
SCHEMBL19107418 0.60 KDM4E (0.53) KDM4EGMNNPPM1BLMNAPPP1CC
SCHEMBL112827 0.60 KDM4E (0.53) KDM4EGMNNPPM1BLMNAPPP1CC
SCHEMBL21999910 0.60 KDM4E (0.53) KDM4EGMNNPPM1BLMNAPPP1CC
SCHEMBL910480 0.60 KDM4E (0.53) KDM4EGMNNPPM1BLMNAPPP1CC
SCHEMBL16923832 0.60 KDM4E (0.53) KDM4EGMNNPPM1BLMNAPPP1CC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 240 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119081040-A Preparation method of chemically recyclable polyacetal and product and chemical recycling method thereof 浙江大学 2024-12-06 CN claimed
CN-118994284-A Gemcitabine prodrug or pharmaceutically acceptable salt thereof containing side chains with different flexibilities, self-assembled nanoparticle thereof and application 沈阳药科大学 2024-11-22 CN claimed
CN-118955886-A Carbonate functionalized polymer and synthetic method and application thereof 华南理工大学 2024-11-15 CN claimed
US-20240368726-A1 THIODIGLYCOLAMIC ACID EXTRACTANT, AND PREPARATION METHOD AND USE THEREOF INSTITUTE OF APPLIED CHEMISTRY, JIANGXI ACADEMY OF SCIENCES (CN) 2024-11-07 US claimed
CN-118702912-A Preparation method of spontaneously degradable cyclic poly (ester-peptide), product and degradation method thereof 浙江大学 2024-09-27 CN claimed
CN-118406203-A Preparation method of intrinsic flame-retardant high-strength polyacetal and product thereof 浙江大学 2024-07-30 CN claimed
CN-118271570-A Preparation method of organic phosphine-terminated non-conjugated oxygen-enriched fluorescent polymer, and product and application thereof 浙江大学 2024-07-02 CN claimed
CN-118184555-A Method for synthesizing and purifying HDEHSDGA 山东第一医科大学(山东省医学科学院) 2024-06-14 CN claimed
CN-117736254-A N, N-dimethyl ethylenediamine-thiodiglycolic acid mono-cholesterol ester conjugate and preparation method and application thereof 常州大学 2024-03-22 CN claimed
CN-114853617-B Extracting agent for extracting and separating neodymium (III), preparation method and application thereof 山东大学 2023-12-22 CN claimed
CN-106729746-B To the preparation method and applications of the tumor infiltrating nanosystems of the partial size shrinkage type of FAP- α enzyme, reducing environment sensitive 郑州大学 2019-11-22 CN claimed
CN-106602141-B A kind of electrolyte and secondary cell 宁德新能源科技有限公司 2019-01-08 CN claimed
CN-108478794-A The structure of photosensitizer-chemotherapeutic \" photochemical one \" small molecule prodrugs and its self-assembled nanometer grain 沈阳药科大学 2018-09-04 CN claimed
CN-106729746-A To FAP α enzymes, the preparation method and applications of the tumor infiltrating nanosystems of the particle diameter shrinkage type of reducing environment sensitive 郑州大学 2017-05-31 CN claimed
CN-106602141-A Electrolyte and secondary battery 宁德新能源科技有限公司 2017-04-26 CN claimed
WO-2016116335-A1 ENZYMATIC PROCESS FOR THE REGIOSELECTIVE MANUFACTURING OF N-FMOC-DOXORUBICIN-14-O-DICARBOXYLIC ACID MONO ESTERS AETERNA ZENTARIS GMBH (DE) 2016-07-28 WO claimed
US-20160208298-A1 ENZYMATIC PROCESS FOR THE REGIOSELECTIVE MANUFACTURING OF N-FMOC-DOXORUBICIN-14-O-DICARBOXYLIC ACID MONO ESTERS AETERNA ZENTARIS GMBH (DE) 2016-07-21 US claimed
EP-3045540-A1 Enzymatic process for the regioselective manufacturing of N-Fmoc-doxorubicin-14-O-dicarboxylic acid mono esters Æterna Zentaris GmbH (DE) 2016-07-20 EP claimed
US-4323676-A Process for preparing cephalosporins TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1982-04-06 US claimed
US-4308381-A Cephem compounds TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1981-12-29 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240368726-A1 THIODIGLYCOLAMIC ACID EXTRACTANT, AND PREPARATION METHOD AND USE THEREOF GDA, AGL, MGAM KDM4E 3489/4885GMNN 258/4885PPM1B 4008/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.