SCHEMBL6045969

SCHEMBL6045969

O=C1OC(=O)C(O)SSC1O

nearest known ligand 0.31

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.31
GMNN O75496 1/20 0.31
PPM1B O75688 1/20 0.31
LMNA P02545 1/20 0.31
PPP1CC P36873 1/20 0.31
TFPI2 P48307 1/20 0.31
RAB9A P51151 1/20 0.31
PPP5C P53041 1/20 0.31
PPP1CA P62136 1/20 0.31
PMP22 Q01453 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
TP53 P04637 1/20 0.31
CYP2D6 P10635 1/20 0.31
NFKB1 P19838 1/20 0.31
THPO P40225 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1014782 0.81 KDM4E (0.31) KDM4EGMNNPPM1BLMNAPPP1CC
SCHEMBL375777 0.69
SCHEMBL2470524 0.69
SCHEMBL4165018 0.65 LMNA (0.42) KDM4EGMNNPPM1BLMNAPPP1CC
SCHEMBL11752874 0.62
SCHEMBL19107418 0.60 KDM4E (0.53) KDM4EGMNNPPM1BLMNAPPP1CC
SCHEMBL910480 0.60 KDM4E (0.53) KDM4EGMNNPPM1BLMNAPPP1CC
SCHEMBL14187990 0.60 KDM4E (0.38) KDM4EGMNNPPM1BLMNAPPP1CC
SCHEMBL21999910 0.60 KDM4E (0.53) KDM4EGMNNPPM1BLMNAPPP1CC
SCHEMBL16923832 0.60 KDM4E (0.53) KDM4EGMNNPPM1BLMNAPPP1CC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113461754-B Base-modified adriamycin prodrug and preparation method and application thereof 沈阳药科大学 2022-08-23 CN claimed
CN-113461754-A Base-modified adriamycin prodrug and preparation method and application thereof 沈阳药科大学 2021-10-01 CN claimed
CN-109771661-B Oxcetitinib brain-targeted drug delivery system and application thereof in resisting lung cancer brain metastasis tumor 南京医科大学 2021-08-31 CN claimed
CN-113461754-B Base-modified adriamycin prodrug and preparation method and application thereof 沈阳药科大学 2022-08-23 CN disclosed
CN-114129735-A Cabazitaxel-fatty acid conjugate and nano preparation thereof 苏州裕泰医药科技有限公司 2022-03-04 CN disclosed
CN-113461754-A Base-modified adriamycin prodrug and preparation method and application thereof 沈阳药科大学 2021-10-01 CN disclosed
CN-109771661-B Oxcetitinib brain-targeted drug delivery system and application thereof in resisting lung cancer brain metastasis tumor 南京医科大学 2021-08-31 CN disclosed
US-20060141632-A1 New methods and kits for sequencing polypeptides THE PROCTER & GAMBLE CO. 2006-06-29 US disclosed
EP-1145012-B1 METHODS AND KITS FOR SEQUENCING POLYPEPTIDES PROCTER & GAMBLE (US) 2004-08-18 EP disclosed
EP-1356297-A2 METHODS AND KITS FOR SEQUENCING POLYPEPTIDES THE PROCTER & GAMBLE COMPANY (US) 2003-10-29 EP disclosed
WO-2002008767-A2 METHODS AND KITS FOR SEQUENCING POLYPEPTIDES THE PROCTER & GAMBLE COMPANY (US) 2002-01-31 WO disclosed