SCHEMBL910480

SCHEMBL910480

O=C1OC(=O)C2C3C(=O)OC(=O)C2C13

nearest known ligand 0.53

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.53
GMNN O75496 1/20 0.53
PPM1B O75688 1/20 0.53
LMNA P02545 1/20 0.53
PPP1CC P36873 1/20 0.53
TFPI2 P48307 1/20 0.53
RAB9A P51151 1/20 0.53
PPP5C P53041 1/20 0.53
PPP1CA P62136 1/20 0.53
PMP22 Q01453 1/20 0.53
SMN1; SMN2 Q16637 1/20 0.53
TDP1 Q9NUW8 1/20 0.53
TP53 P04637 1/20 0.53
CYP2D6 P10635 1/20 0.53
NFKB1 P19838 1/20 0.53
THPO P40225 1/20 0.53
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19107418 1.00 KDM4E (0.53) KDM4EGMNNPPM1BLMNAPPP1CC
SCHEMBL16923832 1.00 KDM4E (0.53) KDM4EGMNNPPM1BLMNAPPP1CC
SCHEMBL14649625 1.00 KDM4E (0.53) KDM4EGMNNPPM1BLMNAPPP1CC
SCHEMBL17918621 1.00 KDM4E (0.53) KDM4EGMNNPPM1BLMNAPPP1CC
SCHEMBL17916071 1.00 KDM4E (0.53) KDM4EGMNNPPM1BLMNAPPP1CC
SCHEMBL21999910 1.00 KDM4E (0.53) KDM4EGMNNPPM1BLMNAPPP1CC
SCHEMBL112827 1.00 KDM4E (0.53) KDM4EGMNNPPM1BLMNAPPP1CC
SCHEMBL1363045 0.84 KDM4E (0.48) KDM4EGMNNPPM1BLMNAPPP1CC
SCHEMBL12799496 0.84 KDM4E (0.48) KDM4EGMNNPPM1BLMNAPPP1CC
SCHEMBL2699713 0.83 KDM4E (0.42) KDM4EGMNNPPM1BLMNAPPP1CC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1813592-B1 CAGE-SHAPED CYCLOBUTANOIC DIANHYDRIDES AND PROCESS FOR PRODUCTION THEREOF NISSAN CHEMICAL IND LTD (JP) 2012-10-10 EP claimed
US-7872148-B2 Cage-shaped cyclobutanoic dianhydrides and process for production thereof NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2011-01-18 US claimed
US-20090012318-A1 Cage-shaped cyclobutanoic dianhydrides and process for production thereof NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2009-01-08 US claimed
EP-1813592-A1 CAGE-SHAPED CYCLOBUTANOIC DIANHYDRIDES AND PROCESS FOR PRODUCTION THEREOF Nissan Chemical Industries, Ltd. (JP) 2007-08-01 EP claimed
US-20180127655-A1 LIQUID CRYSTAL ALIGNING AGENTS FOR FORMING PHOTO-ALIGNING LIQUID CRYSTAL ALIGNMENT LAYERS, LIQUID CRYSTAL ALIGNMENT LAYERS AND LIQUID CRYSTAL DISPLAY DEVICES USING THE SAME JNC CORPORATION (JP) 2018-05-10 US disclosed
US-9909065-B2 Liquid crystal aligning agents for forming photo-aligning liquid crystal alignment layers, liquid crystal alignment layers and liquid crystal display devices using the same JNC CORPORATION (JP) 2018-03-06 US disclosed
US-20170327743-A1 LIQUID CRYSTAL DISPLAY DEVICE AND METHOD FOR MANUFACTURING SAME JNC CORP (JP) 2017-11-16 US disclosed
US-20170327743-A1 LIQUID CRYSTAL DISPLAY DEVICE AND METHOD FOR MANUFACTURING SAME JNC CORP (JP) 2017-11-16 US disclosed
US-9796927-B2 Liquid crystal aligning agents for forming photo-aligning liquid crystal alignment layers, liquid crystal alignment layers and liquid crystal display devices using the same JNC CORPORATION (JP) 2017-10-24 US disclosed
US-9771519-B2 Liquid crystal display device and method for manufacturing same JNC CORPORATION (JP) 2017-09-26 US disclosed
US-20160369168-A1 LIQUID CRYSTAL DISPLAY DEVICE JNC CORPORATION (JP) 2016-12-22 US disclosed
US-20150275089-A1 LIQUID CRYSTAL DISPLAY ELEMENT AND METHOD FOR MANUFACTURING SAME JNC PETROCHEMICAL CORPORATION (JP) 2015-10-01 US disclosed
US-20100063243-A1 POLYAMIC ACIDS, POLYIMIDES, AND PROCESSES FOR THE PRODUCTION THEREOF NISSAN CHEMICAL INDUSTRIES LTD (JP) 2010-03-11 US disclosed
US-20090012318-A1 Cage-shaped cyclobutanoic dianhydrides and process for production thereof NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2009-01-08 US disclosed
US-20090012318-A1 Cage-shaped cyclobutanoic dianhydrides and process for production thereof NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2009-01-08 US disclosed
US-20090012318-A1 Cage-shaped cyclobutanoic dianhydrides and process for production thereof NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2009-01-08 US disclosed
EP-1813592-A1 CAGE-SHAPED CYCLOBUTANOIC DIANHYDRIDES AND PROCESS FOR PRODUCTION THEREOF Nissan Chemical Industries, Ltd. (JP) 2007-08-01 EP disclosed
EP-1813592-A1 CAGE-SHAPED CYCLOBUTANOIC DIANHYDRIDES AND PROCESS FOR PRODUCTION THEREOF Nissan Chemical Industries, Ltd. (JP) 2007-08-01 EP disclosed
EP-1813592-A1 CAGE-SHAPED CYCLOBUTANOIC DIANHYDRIDES AND PROCESS FOR PRODUCTION THEREOF Nissan Chemical Industries, Ltd. (JP) 2007-08-01 EP disclosed
WO-2006043519-A1 CAGE-SHAPED CYCLOBUTANOIC DIANHYDRIDES AND PROCESS FOR PRODUCTION THEREOF NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2006-04-27 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090012318-A1 Cage-shaped cyclobutanoic dianhydrides and process for production thereof ADH1C, ADH1A, ADH5 KDM4E 3480/4885GMNN 4625/4885PPM1B 3054/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.