Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR1 | Q92633 | 1/20 | 0.57 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.57 |
| ▸ | HTR1A | P08908 | 4/20 | 0.48 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.48 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.48 |
| ▸ | ACSL1 | P33121 | 3/20 | 0.44 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.43 |
| ▸ | ACSL3 | O95573 | 1/20 | 0.43 |
| ▸ | ACSL6 | Q9UKU0 | 1/20 | 0.43 |
| ▸ | PDE4A | P27815 | 1/20 | 0.43 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.43 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.42 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.42 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.42 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16506413 | 1.00 | LPAR1 (0.57) | LPAR1LPAR5HTR1ASLC6A2SLC6A3 | |
| SCHEMBL28011392 | 0.88 | SLC6A2 (0.54) | LPAR1LPAR5HTR1ASLC6A2SLC6A3 | |
| SCHEMBL29966 | 0.84 | SLC6A2 (0.61) | LPAR1LPAR5HTR1ASLC6A2SLC6A3 | |
| SCHEMBL2473263 | 0.83 | LPAR1 (0.51) | LPAR1LPAR5HTR1ASLC6A2SLC6A3 | |
| SCHEMBL2473260 | 0.83 | LPAR1 (0.51) | LPAR1LPAR5HTR1ASLC6A2SLC6A3 | |
| SCHEMBL2473607 | 0.82 | LPAR1 (0.50) | LPAR1LPAR5HTR1ASLC6A2SLC6A3 | |
| SCHEMBL2473606 | 0.82 | LPAR1 (0.50) | LPAR1LPAR5HTR1ASLC6A2SLC6A3 | |
| SCHEMBL16507018 | 0.81 | LPAR1 (0.52) | LPAR1LPAR5HPGD | |
| SCHEMBL10148356 | 0.81 | LPAR1 (0.52) | LPAR1LPAR5HPGD | |
| SCHEMBL16506986 | 0.81 | PDE4A (0.59) | LPAR1LPAR5ACSL1ACSL3ACSL6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120046292-A1 | DIACYLETHYLENEDIAMINE COMPOUND | ASTELLAS PHARMA INC. (JP) | 2012-02-23 | — | — | US | disclosed |
| US-20120046292-A1 | DIACYLETHYLENEDIAMINE COMPOUND | ASTELLAS PHARMA INC. (JP) | 2012-02-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120046292-A1 | DIACYLETHYLENEDIAMINE COMPOUND | DGAT1, DGAT2, DIMT1 | LPAR1 1629/4885LPAR5 2217/4885HTR1A 2176/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.