Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 3/20 | 0.47 |
| ▸ | RXRB | P28702 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | MAPT | P10636 | 6/20 | 0.43 |
| ▸ | PKM | P14618 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.39 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | THRB | P10828 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.39 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.38 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10123702 | 0.80 | RXRA (0.44) | RXRARXRBALDH1A1MAPTPKM | |
| SCHEMBL10148986 | 0.78 | RXRA (0.44) | RXRARXRBALDH1A1MAPTPKM | |
| SCHEMBL10148487 | 0.69 | KDM4E (0.38) | RXRARXRBALDH1A1MAPTPKM | |
| SCHEMBL3639186 | 0.66 | RXRA (1.00) | RXRARXRBALDH1A1SMN1; SMN2TP53 | |
| SCHEMBL7923941 | 0.65 | MAP4K4 (0.56) | RXRARXRBALDH1A1MAPTSMN1; SMN2 | |
| Aminobenzoic Acid SCHEMBL17712652 | 0.65 | RXRA (0.62) | RXRARXRBALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL13522875 | 0.64 | ALDH1A1 (0.63) | RXRARXRBALDH1A1SMN1; SMN2MAP4K4 | |
| Terephthalic Acid SCHEMBL27850877 | 0.63 | TPMT (0.76) | RXRARXRBALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL13888048 | 0.63 | ALDH1A1 (0.85) | RXRARXRBALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL308875 | 0.63 | ALDH1A1 (0.85) | RXRARXRBALDH1A1MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2415771-A1 | INDOLIZINE DERIVATIVE AND USE THEREOF FOR MEDICAL PURPOSES | Kissei Pharmaceutical Co., Ltd. (JP) | 2012-02-08 | — | — | EP | disclosed |