SCHEMBL10148969

SCHEMBL10148969

CCCc1ccc2c(c1)c1cc(C(C)C)ccc1n2-c1ccc(-c2nnc3c4ccccc4ccn23)cc1

nearest known ligand 0.41

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
UCHL3 P15374 2/20 0.41
RORA P35398 1/20 0.36
RORC P51449 1/20 0.36
RORB Q92753 1/20 0.36
HCRTR1 O43613 1/20 0.30
TP53 P04637 1/20 0.30
MAPT P10636 1/20 0.30
ALOX15 P16050 1/20 0.30
MAPK1 P28482 1/20 0.30
RAB9A P51151 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30
PTAFR P25105 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10128228 0.93 HSD11B1 (0.34) UCHL3RORARORCRORBHCRTR1
SCHEMBL10128229 0.91 RORA (0.35) UCHL3RORARORCRORBMAPT
SCHEMBL10128230 0.87 HSD11B1 (0.42) UCHL3RORARORCRORBHCRTR1
SCHEMBL10128231 0.85 RXFP1 (0.34) UCHL3RORARORCRORBHCRTR1
SCHEMBL10128226 0.85 MAPT (0.37) RORARORCRORBHCRTR1TP53
SCHEMBL10155413 0.85 ALDH1A1 (0.35) UCHL3RORARORCRORBMAPT
SCHEMBL10128234 0.84 DRD1 (0.33) UCHL3HCRTR1TP53MAPTALOX15
SCHEMBL10148967 0.79 MAPT (0.37) RORARORCRORBMAPT
SCHEMBL10148971 0.79 MAPT (0.36) RORARORCRORBHCRTR1TP53
SCHEMBL10128221 0.79 ALDH1A1 (0.41) MAPTMAPK1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2012017842-A1 TRIAZOLE DERIVATIVE, HETEROCYCLIC COMPOUND, LIGHT-EMITTING ELEMENT, LIGHT-EMITTING DEVICE, ELECTRONIC DEVICE AND LIGHTING DEVICE SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2012-02-09 WO disclosed