Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | MMP8 | P22894 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | KIF11 | P52732 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.39 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.39 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.39 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.39 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.39 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.39 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1003915 | 0.78 | CA12 (0.52) | CA1CA12MMP8TDP1MAPT | |
| SCHEMBL14034732 | 0.76 | KIF11 (0.46) | CA1MAPTKIF11CA2MEN1 | |
| SCHEMBL24260756 | 0.74 | CA12 (0.48) | CA1CA12MMP8TDP1MAPT | |
| SCHEMBL22399126 | 0.74 | CA12 (0.48) | CA1CA12MMP8TDP1MAPT | |
| SCHEMBL21169612 | 0.74 | CA12 (0.48) | CA1CA12MMP8TDP1MAPT | |
| SCHEMBL9501161 | 0.74 | CA1 (0.52) | CA1CA12MMP8TDP1MAPT | |
| SCHEMBL447463 | 0.73 | CA12 (0.47) | CA1CA12MMP8TDP1MAPT | |
| SCHEMBL3141077 | 0.72 | CA1 (0.50) | CA1CA12MMP8TDP1MAPT | |
| SCHEMBL1454276 | 0.72 | TDP1 (0.59) | CA1CA12MMP8TDP1MAPT | |
| SCHEMBL3952756 | 0.71 | CA1 (0.46) | CA1CA12MMP8TDP1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2422788-A2 | Benzodiazepines and compositions and uses thereof | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2012-02-29 | — | — | EP | disclosed |