Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | MMP8 | P22894 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | THRB | P10828 | 2/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
| ▸ | CASP1 | P29466 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1454276 | 0.83 | TDP1 (0.59) | CA1CA12MMP8MAPTTDP1 | |
| SCHEMBL9501161 | 0.80 | CA1 (0.52) | CA1CA12MMP8MAPTTDP1 | |
| SCHEMBL20670400 | 0.79 | CA1 (0.47) | CA1CA12MMP8MAPTTDP1 | |
| SCHEMBL1003915 | 0.79 | CA12 (0.52) | CA1CA12MMP8MAPTTDP1 | |
| SCHEMBL18559184 | 0.79 | MAPT (0.50) | CA1CA12MMP8MAPTTDP1 | |
| SCHEMBL23485010 | 0.79 | CA1 (0.47) | CA1CA12MMP8MAPTTDP1 | |
| SCHEMBL28422646 | 0.79 | MAPT (0.44) | CA1CA12MMP8MAPTTDP1 | |
| SCHEMBL16574223 | 0.77 | ALDH1A1 (0.50) | CA1CA12MMP8MAPTTDP1 | |
| SCHEMBL675141 | 0.77 | TDP1 (0.68) | CA1CA12MMP8MAPTTDP1 | |
| SCHEMBL3130813 | 0.76 | NFKB1 (0.45) | CA1CA12MAPTTDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010042250-A2 | SEMIPERMEABLE POLYMERS AND METHOD FOR PRODUCING SAME | ELTRON RESEARCH AND DEVELOPMENT, INC. (US) | 2010-04-15 | — | — | WO | disclosed |