SCHEMBL10150820

SCHEMBL10150820

O=C1C2CC3CC1CC(OC(=O)C(F)(F)S(=O)(=O)O/N=C(/c1ccccc1)C(F)(F)F)(C3)C2

nearest known ligand 0.38

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.38
NPSR1 Q6W5P4 1/20 0.38
CYP17A1 P05093 1/20 0.32
CYP19A1 P11511 1/20 0.32
CASR P41180 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10150846 0.89 TSHR (0.35) TSHRNPSR1
SCHEMBL10150840 0.83 NPSR1 (0.36) TSHRNPSR1CYP17A1CYP19A1
SCHEMBL1593389 0.79 TSHR (0.41) TSHRNPSR1CYP17A1CYP19A1CASR
SCHEMBL10150823 0.78 P2RX7 (0.38)
SCHEMBL26190608 0.75 TSHR (0.48) TSHRNPSR1CYP17A1CYP19A1
SCHEMBL26191698 0.74 TSHR (0.40) TSHRNPSR1CYP17A1CYP19A1
SCHEMBL19261603 0.74 TSHR (0.52) TSHRNPSR1CYP17A1CYP19A1
SCHEMBL547287 0.74 TSHR (0.52) TSHRNPSR1CYP17A1CYP19A1
SCHEMBL10186087 0.74 SRC (0.41) TSHR
SCHEMBL10150826 0.74 SRC (0.41) TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8173350-B2 Oxime compound and resist composition containing the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-05-08 US disclosed
US-20100021847-A1 Oxime Compound and Resist Composition Containing the Same SUMITOMO CHEMICAL COMPANY, LTD. (JP) 2010-01-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100021847-A1 Oxime Compound and Resist Composition Containing the Same CYC1, UQCRB, CBR1 TSHR 841/4885NPSR1 2324/4885CYP17A1 121/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.