SCHEMBL10151497

SCHEMBL10151497

C/C(C#N)=C1\CC(=O)c2ccccc21

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.40
MAOA P21397 1/20 0.35
NOTUM Q6P988 1/20 0.35
KMT2A Q03164 5/20 0.33
MEN1 O00255 4/20 0.33
USP8 P40818 1/20 0.33
USP7 Q93009 1/20 0.33
CDC25B P30305 1/20 0.33
PIM1 P11309 1/20 0.33
BCHE P06276 1/20 0.33
CES1 P23141 1/20 0.33
HPGD P15428 3/20 0.33
KDM4E B2RXH2 3/20 0.33
L3MBTL1 Q9Y468 1/20 0.32
CYP3A4 P08684 1/20 0.31
MAPT P10636 1/20 0.31
PABPC1 P11940 1/20 0.31
BLM P54132 1/20 0.31
POLB P06746 1/20 0.31
S100A4 P26447 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29444282 0.81 MAPT (0.38) ALDH1A1MAOAKMT2AMEN1PIM1
SCHEMBL806906 0.81 MAPT (0.38) ALDH1A1MAOAKMT2AMEN1PIM1
SCHEMBL14141263 0.80 GAA (0.37) ALDH1A1KMT2AMEN1KDM4EMAPT
SCHEMBL30464047 0.80 MAPT (0.37) ALDH1A1MAOAKMT2AMEN1PIM1
SCHEMBL14600848 0.80 S100A4 (0.35) ALDH1A1MAOAKMT2AMEN1USP8
Ammonia Solution, Strong SCHEMBL29011557 0.80 MAPT (0.37) ALDH1A1MAOAKMT2AMEN1PIM1
SCHEMBL10046603 0.79 ALDH1A1 (0.55) ALDH1A1MAOANOTUMKMT2AMEN1
SCHEMBL20042500 0.79 ALDH1A1 (0.37) ALDH1A1MAOAKMT2AMEN1USP8
SCHEMBL9970445 0.75 PIM1 (0.31) ALDH1A1PIM1BCHECES1HPGD
SCHEMBL31607080 0.75 PIM1 (0.31) ALDH1A1PIM1BCHECES1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220149298-A1 PHOTOACTIVE COMPOUNDS FOR VAPOR DEPOSITED ORGANIC PHOTOVOLTAIC DEVICES UBIQUITOUS ENERGY, INC. (US) 2022-05-12 US disclosed
US-20220135587-A1 PHOTOACTIVE COMPOUNDS FOR VAPOR DEPOSITED ORGANIC PHOTOVOLTAIC DEVICES UBIQUITOUS ENERGY, INC. (US) 2022-05-05 US disclosed
US-20220140266-A1 PHOTOACTIVE COMPOUNDS FOR VAPOR DEPOSITED ORGANIC PHOTOVOLTAIC DEVICES UBIQUITOUS ENERGY, INC. (US) 2022-05-05 US disclosed
EP-2261270-B1 Polymer, producing method thereof, and photorefractive composition NITTO DENKO CORP (JP) 2012-05-09 EP disclosed
EP-2261270-A1 Polymer, producing method thereof, and photorefractive composition Nitto Denko Corporation (JP) 2010-12-15 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220140266-A1 PHOTOACTIVE COMPOUNDS FOR VAPOR DEPOSITED ORGANIC PHOTOVOLTAIC DEVICES VIM, ALDH1A2, ICAM1 ALDH1A1 30/4885MAOA 2886/4885NOTUM 1598/4885
US-20220149298-A1 PHOTOACTIVE COMPOUNDS FOR VAPOR DEPOSITED ORGANIC PHOTOVOLTAIC DEVICES VIM, ALDH1A2, ICAM1 ALDH1A1 30/4885MAOA 2886/4885NOTUM 1598/4885
US-20220135587-A1 PHOTOACTIVE COMPOUNDS FOR VAPOR DEPOSITED ORGANIC PHOTOVOLTAIC DEVICES VIM, ALDH1A2, ICAM1 ALDH1A1 30/4885MAOA 2886/4885NOTUM 1598/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.