Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | SPHK1 | Q9NYA1 | 6/20 | 0.38 |
| ▸ | SPHK2 | Q9NRA0 | 5/20 | 0.38 |
| ▸ | GBA1 | P04062 | 3/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | NOS3 | P29474 | 1/20 | 0.35 |
| ▸ | NOS1 | P29475 | 1/20 | 0.35 |
| ▸ | NOS2 | P35228 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | EBP | Q15125 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7908546 | 0.86 | ALDH1A1 (0.52) | ALDH1A1EPHX1ALOX5SPHK1SPHK2 | |
| SCHEMBL7909283 | 0.79 | ALDH1A1 (0.42) | ALDH1A1EPHX1ALOX5SPHK1SPHK2 | |
| SCHEMBL4557504 | 0.77 | ALOX5 (0.50) | ALDH1A1EPHX1ALOX5GBA1CYP1A2 | |
| SCHEMBL1437889 | 0.77 | ALOX5 (0.50) | ALDH1A1EPHX1ALOX5GBA1CYP1A2 | |
| SCHEMBL1573174 | 0.77 | ALOX5 (0.50) | ALDH1A1EPHX1ALOX5GBA1CYP1A2 | |
| SCHEMBL8539157 | 0.76 | ALDH1A1 (0.48) | ALDH1A1EPHX1ALOX5SPHK1SPHK2 | |
| SCHEMBL11691475 | 0.75 | ALDH1A1 (0.56) | ALDH1A1EPHX1SPHK1SPHK2GBA1 | |
| SCHEMBL11727901 | 0.75 | ALDH1A1 (0.56) | ALDH1A1EPHX1SPHK1SPHK2GBA1 | |
| SCHEMBL11810911 | 0.75 | ALDH1A1 (0.56) | ALDH1A1EPHX1SPHK1SPHK2GBA1 | |
| SCHEMBL15456660 | 0.74 | ALDH1A1 (0.56) | ALDH1A1EPHX1ALOX5SPHK1SPHK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1955697-B1 | 2-AMINOBENZAMIDE DERIVATIVES AS VANILLOID RECEPTOR 1 (VR1) INHIBITORS USEFUL FOR THE TREATMENT OF PAIN OR BLADDER FUNCTION DISORDER | ASTELLAS PHARMA INC (JP) | 2012-05-02 | — | — | EP | disclosed |