Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | SPHK1 | Q9NYA1 | 7/20 | 0.38 |
| ▸ | SPHK2 | Q9NRA0 | 6/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.35 |
| ▸ | GBA1 | P04062 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | GUSB | P08236 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7909283 | 0.92 | ALDH1A1 (0.42) | ALDH1A1EPHX1ALOX5SPHK1SPHK2 | |
| SCHEMBL10151503 | 0.86 | ALDH1A1 (0.50) | ALDH1A1EPHX1ALOX5SPHK1SPHK2 | |
| SCHEMBL11513898 | 0.81 | ALOX5 (0.67) | ALDH1A1ALOX5CYP1A2TSHRTDP1 | |
| SCHEMBL7914648 | 0.80 | CA1 (0.39) | ALDH1A1GBA1 | |
| SCHEMBL10697801 | 0.79 | — | — | |
| SCHEMBL11691475 | 0.77 | ALDH1A1 (0.56) | ALDH1A1EPHX1SPHK1SPHK2CYP1A2 | |
| SCHEMBL11810911 | 0.77 | ALDH1A1 (0.56) | ALDH1A1EPHX1SPHK1SPHK2CYP1A2 | |
| SCHEMBL11727901 | 0.77 | ALDH1A1 (0.56) | ALDH1A1EPHX1SPHK1SPHK2CYP1A2 | |
| SCHEMBL8539157 | 0.75 | ALDH1A1 (0.48) | ALDH1A1EPHX1ALOX5SPHK1SPHK2 | |
| SCHEMBL5558474 | 0.75 | EPHX1 (0.41) | ALDH1A1EPHX1SPHK1SPHK2CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6201137-B1 | CONTACTING CRUDE TETRAHYDROFURAN WITH MINERAL ACID SELECTED FROM THE GROUP CONSISTING OF NITRIC ACID, SULFURIC ACID, AND PHOSPHORIC ACID, THEN INSTANTLY DISTILLATING | HODOGAYA CHEMICAL CO., LTD. (JP) | 2001-03-13 | — | — | US | disclosed |