Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SNCA | P37840 | 1/20 | 0.58 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.58 |
| ▸ | MEN1 | O00255 | 5/20 | 0.58 |
| ▸ | MAPT | P10636 | 3/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.58 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.58 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.57 |
| ▸ | ULK1 | O75385 | 1/20 | 0.55 |
| ▸ | NAMPT | P43490 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.53 |
| ▸ | ME3 | Q16798 | 1/20 | 0.52 |
| ▸ | FLT3 | P36888 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | GFER | P55789 | 1/20 | 0.51 |
| ▸ | MGLL | Q99685 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14618675 | 0.87 | NAMPT (0.69) | KMT2AMEN1MAPTALDH1A1ALOX15 | |
| SCHEMBL13144615 | 0.85 | ALDH1A1 (0.58) | KMT2AMEN1MAPTALDH1A1HTT | |
| SCHEMBL31098663 | 0.85 | SIRT2 (0.56) | KMT2AMEN1MAPTALOX15HTT | |
| SCHEMBL18395563 | 0.85 | KMT2A (0.58) | KMT2AMEN1ALOX15HTTSIRT2 | |
| SCHEMBL13707510 | 0.85 | SIRT2 (0.56) | SNCADYRK1AKMT2AMEN1MAPT | |
| SCHEMBL2717891 | 0.85 | ULK1 (0.60) | SNCADYRK1AKMT2AMEN1MAPT | |
| SCHEMBL4677821 | 0.85 | KMT2A (0.63) | KMT2AMEN1HTTSIRT2ULK1 | |
| SCHEMBL4141969 | 0.84 | HPGD (0.69) | KMT2AMEN1MAPTSIRT2ULK1 | |
| SCHEMBL31198189 | 0.84 | PTPN1 (0.68) | KMT2AMEN1MAPTALDH1A1ALOX15 | |
| Hydrochloric Acid SCHEMBL4714884 | 0.83 | KMT2A (0.56) | KMT2AMEN1ALOX15HTTSIRT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2404902-A1 | PIPERIDINE AND PYRROLIDINE DERIVATIVES HAVING NPY Y5 RECEPTOR ANTAGONISM | Shionogi&Co., Ltd. (JP) | 2012-01-11 | — | — | EP | disclosed |