SCHEMBL4141969

SCHEMBL4141969

O=C(Nc1ccccc1)C1CCNCC1

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 1/20 0.69
MAPT P10636 3/20 0.67
GAA P10253 3/20 0.67
MEN1 O00255 2/20 0.67
KMT2A Q03164 2/20 0.67
GFER P55789 1/20 0.67
SIRT2 Q8IXJ6 1/20 0.62
GLA P06280 1/20 0.59
F10 P00742 1/20 0.57
KDM4E B2RXH2 1/20 0.57
NPC1 O15118 1/20 0.57
LMNA P02545 1/20 0.57
CASP3 P42574 1/20 0.57
RAB9A P51151 1/20 0.57
SMN1; SMN2 Q16637 1/20 0.57
SENP7 Q9BQF6 1/20 0.57
KCNK3 O14649 1/20 0.54
KCNK9 Q9NPC2 1/20 0.54
YAP1 P46937 1/20 0.54
TEAD4 Q15561 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL8508299 0.98 HPGD (0.67) HPGDMAPTGAAMEN1KMT2A
SCHEMBL1318504 0.90 HPGD (0.60) HPGDMAPTGAAMEN1KMT2A
SCHEMBL14505992 0.90 HPGD (0.60) HPGDMAPTGAAMEN1KMT2A
Hydrochloric Acid SCHEMBL1320464 0.88 HPGD (0.58) HPGDMAPTGAAMEN1KMT2A
SCHEMBL28461389 0.88 GAA (0.65) HPGDMAPTGAAMEN1KMT2A
SCHEMBL501924 0.87 GAA (0.85) HPGDMAPTGAAMEN1KMT2A
SCHEMBL10055001 0.87 GAA (0.85) HPGDMAPTGAAMEN1KMT2A
SCHEMBL29675219 0.87 GAA (0.85) HPGDMAPTGAAMEN1KMT2A
SCHEMBL19494423 0.86 MTNR1A (0.64) HPGDMAPTGAAMEN1KMT2A
Hydrochloric Acid SCHEMBL19468406 0.85 MTNR1A (0.62) HPGDMAPTGAAMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 91 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240018135-A1 COMPOUND HAVING INHIBITORY ACTIVITY AGAINST O-GLUSACASE AND USE THEREOF MEDIFRON DBT INC. (KR) 2024-01-18 US claimed
CN-117396463-A Benzamide derivative for preventing or treating cancer, method for preparing the same, and pharmaceutical composition containing the same as active ingredient 怡诺安有限公司 2024-01-12 CN claimed
WO-2022245061-A1 BENZAMIDE DERIVATIVE, METHOD FOR PREPARING SAME, AND PHARMACEUTICAL COMPOSITION FOR PREVENTION OR TREATMENT OF CANCER CONTAINING SAME AS ACTIVE INGREDIENT 에이치케이이노엔 주식회사 2022-11-24 WO claimed
EP-4719413-A1 INHIBITORS OF CANINE JANUS KINASE AND USES THEREOF Animol Discovery, Inc. (US) 2026-04-08 EP disclosed
US-20260092070-A1 INHIBITORS OF CANINE JANUS KINASE AND USES THEREOF ANIMOL DISCOVERY INC (US) 2026-04-02 US disclosed
US-20250326744-A1 PIPERAZINE DERIVATIVE OR SALT THEREOF, AND PHARMACEUTICAL COMPOSITION FUJIFILM CORPORATION (JP) 2025-10-23 US disclosed
CN-119816484-A Novel piperazine derivative or salt thereof and pharmaceutical composition 富士胶片株式会社 2025-04-11 CN disclosed
WO-2024246837-A1 INHIBITORS OF CANINE JANUS KINASE AND USES THEREOF ANIMOL DISCOVERY, INC. (US) 2024-12-05 WO disclosed
CN-118666840-A Design synthesis and application of spiro [ pyrrolidine-3, 3 '-quinoline ] -2,2' -diketopiperidine carboxamide compound 西南大学 2024-09-20 CN disclosed
US-20240217978-A1 COMPOUND AS ADENOSINE A2a RECEPTOR ANTAGONIST AND PHARMACEUTICAL COMPOSITION COMPRISING SAME CHONG KUN DANG PHARMACEUTICAL CORP. (KR) 2024-07-04 US disclosed
US-20240217978-A1 COMPOUND AS ADENOSINE A2a RECEPTOR ANTAGONIST AND PHARMACEUTICAL COMPOSITION COMPRISING SAME CHONG KUN DANG PHARMACEUTICAL CORP. (KR) 2024-07-04 US disclosed
US-5648366-A TACHYKININ ANTAGONISTS USEFUL IN TREATING ASTHMA MERRELL PHARMACEUTICALS INC. (US) 1997-07-15 US disclosed
US-5635510-A TACHYKININ (ESPECIALLY SUBSTANCE P AND NEUROKININ A) ANTAGONISTS; ANTIINFLAMMATORY AGENTS, ANALGESICS; NERVOUS SYSTEM DISORDERS; BRONCHODILATOR AGENTS MERRELL PHARMACEUTICALS INC. (US) 1997-06-03 US disclosed
WO-1997008155-A1 NOVEL 2,3-DIOXO-1,2,3,4-TETRAHYDRO-QUINOYXALINYL DERIVATIVES NOVARTIS AG (CH) 1997-03-06 WO disclosed
EP-0717739-A1 BICYCLIC AROMATIC COMPOUNDS AS THERAPEUTIC AGENTS Knoll AG (DE) 1996-06-26 EP disclosed
EP-0696280-A1 SUBSTITUTED PYRROLIDIN-3-YL-ALKYL-PIPERIDINES USEFUL AS TACHYKININ ANTAGONISTS MERRELL DOW PHARMA (US) 1996-02-14 EP disclosed
WO-1995007274-A1 BICYCLIC AROMATIC COMPOUNDS AS THERAPEUTIC AGENTS KNOLL AG (DE) 1995-03-16 WO disclosed
WO-1994026735-A1 SUBSTITUTED PYRROLIDIN-3-YL-ALKYL-PIPERIDINES USEFUL AS TACHYKININ ANTAGONISTS MERRELL DOW PHARMACEUTICALS INC. (US) 1994-11-24 WO disclosed
US-4243666-A HYPOTENSIVE AGENTS PFIZER INC. (US) 1981-01-06 US disclosed
US-4045445-A 11-(4-Piperidyl)dibenzo-diazepines AMERICAN CYANAMID COMPANY (US) 1977-08-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240018135-A1 COMPOUND HAVING INHIBITORY ACTIVITY AGAINST O-GLUSACASE AND USE THEREOF OGA, OGT, ENGASE HPGD 3738/4885MAPT 2864/4885GAA 10/4885
US-20260092070-A1 INHIBITORS OF CANINE JANUS KINASE AND USES THEREOF JAK1, JAK3, JAK2 HPGD 3361/4885MAPT 3322/4885GAA 3881/4885
US-20250326744-A1 PIPERAZINE DERIVATIVE OR SALT THEREOF, AND PHARMACEUTICAL COMPOSITION ABCB11, ABCC1, SLC11A2 HPGD 1533/4885MAPT 2498/4885GAA 674/4885
US-20240217978-A1 COMPOUND AS ADENOSINE A2a RECEPTOR ANTAGONIST AND PHARMACEUTICAL COMPOSITION COMPRISING SAME ADORA2A, ADORA1, ADORA2B HPGD 2234/4885MAPT 4359/4885GAA 3161/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.