Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | ELANE | P08246 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | TDO2 | P48775 | 1/20 | 0.41 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.40 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2611112 | 0.80 | PTGS2 (0.46) | NOTUMPTGS2MAPTALDH1A1ELANE | |
| SCHEMBL16297183 | 0.78 | TSHR (0.54) | PTGS2MAPTALDH1A1CYP2C19NPC1 | |
| SCHEMBL16295467 | 0.76 | ROCK2 (0.47) | MAPTTDO2ROCK2NPC1RAB9A | |
| SCHEMBL16296054 | 0.74 | ROCK2 (0.51) | MAPTALDH1A1CYP2C19IDO1TDO2 | |
| SCHEMBL22349806 | 0.73 | PDE4B (0.45) | ALDH1A1ROCK2GAA | |
| SCHEMBL16296374 | 0.73 | ROCK2 (0.52) | MAPTIDO1TDO2ROCK2KMT2A | |
| SCHEMBL5906041 | 0.72 | POLB (0.43) | MAPTALDH1A1CYP3A4CYP2C19ROCK2 | |
| SCHEMBL17626032 | 0.72 | ROCK2 (0.39) | ROCK2 | |
| SCHEMBL16296362 | 0.71 | ROCK2 (0.65) | IDO1ROCK2POLB | |
| SCHEMBL13603854 | 0.71 | NR4A1 (0.39) | NOTUMMAPTALDH1A1ROCK2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10745398-B2 | 2-(het)aryl-substituted fused heterocycle derivatives as pesticides | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2020-08-18 | — | — | US | disclosed |
| US-8101550-B2 | Anthranilic acid diamide derivative with hetero-aromatic and hetero-cyclic substituents | BAYER CROPSCIENCE AG (DE) | 2012-01-24 | — | — | US | disclosed |
| US-20100029478-A1 | ANTHRANILIC ACID DIAMIDE DERIVATIVE WITH HETERO-AROMATIC AND HETERO-CYCLIC SUBSTITUENTS | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2010-02-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10745398-B2 | 2-(het)aryl-substituted fused heterocycle derivatives as pesticides | CYP4X1, CYP1A1, CYP8B1 | NOTUM 1584/4885PTGS2 640/4885MAPT 4754/4885 |
| US-20100029478-A1 | ANTHRANILIC ACID DIAMIDE DERIVATIVE WITH HETERO-AROMATIC AND HETERO-CYCLIC SUBSTITUENTS | DDT, ANTXR2, QDPR | NOTUM 2929/4885PTGS2 2019/4885MAPT 4293/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.