Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLRMT | O00411 | 1/20 | 0.61 |
| ▸ | P2RY2 | P41231 | 5/20 | 0.52 |
| ▸ | RNASEL | Q05823 | 2/20 | 0.51 |
| ▸ | P2RX1 | P51575 | 2/20 | 0.50 |
| ▸ | P2RX3 | P56373 | 2/20 | 0.50 |
| ▸ | P2RX2 | Q9UBL9 | 2/20 | 0.50 |
| ▸ | P2RY4 | P51582 | 1/20 | 0.50 |
| ▸ | P2RY1 | P47900 | 3/20 | 0.49 |
| ▸ | SRC | P12931 | 1/20 | 0.49 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL806950 | 0.92 | POLRMT (0.59) | POLRMTP2RY2RNASELP2RX1P2RX3 | |
| SCHEMBL16479517 | 0.92 | POLRMT (0.59) | POLRMTP2RY2RNASELP2RX1P2RX3 | |
| SCHEMBL25804330 | 0.90 | POLRMT (0.51) | POLRMTP2RY2RNASELP2RY1SRC | |
| SCHEMBL24538808 | 0.87 | POLRMT (0.47) | POLRMTP2RY2P2RX1P2RX3P2RX2 | |
| SCHEMBL23042806 | 0.85 | NT5E (0.52) | POLRMTP2RX1P2RX3ALDH1A1 | |
| SCHEMBL23960110 | 0.84 | POLRMT (0.57) | POLRMTP2RY2RNASELP2RX1P2RX3 | |
| SCHEMBL15682895 | 0.84 | POLRMT (0.55) | POLRMTP2RY2RNASELP2RX1P2RX3 | |
| SCHEMBL16710862 | 0.83 | POLRMT (0.55) | POLRMTP2RY2RNASELP2RX1P2RX3 | |
| SCHEMBL13519829 | 0.83 | POLRMT (0.55) | POLRMTP2RY2RNASELP2RX1P2RX3 | |
| SCHEMBL3699139 | 0.83 | POLRMT (0.55) | POLRMTP2RY2RNASELP2RX1P2RX3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012012776-A1 | METHODS AND COMPOUNDS FOR TREATING PARAMYXOVIRIDAE VIRUS INFECTIONS | GILEAD SCIENCES, INC. (US) | 2012-01-26 | — | — | WO | disclosed |