Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLRMT | O00411 | 1/20 | 0.47 |
| ▸ | P2RY1 | P47900 | 4/20 | 0.41 |
| ▸ | P2RY2 | P41231 | 3/20 | 0.41 |
| ▸ | SRC | P12931 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | DNPH1 | O43598 | 1/20 | 0.41 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.41 |
| ▸ | TRPM2 | O94759 | 1/20 | 0.41 |
| ▸ | LDHA | P00338 | 1/20 | 0.41 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.41 |
| ▸ | FBP1 | P09467 | 1/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.41 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.41 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.41 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.41 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.41 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25804330 | 0.92 | POLRMT (0.51) | POLRMTP2RY1P2RY2SRCSMN1; SMN2 | |
| SCHEMBL23042806 | 0.88 | NT5E (0.52) | POLRMTP2RY11P2RX1P2RX3ALDH1A1 | |
| SCHEMBL10153839 | 0.87 | POLRMT (0.61) | POLRMTP2RY1P2RY2SRCSMN1; SMN2 | |
| SCHEMBL26832023 | 0.82 | POLRMT (0.40) | POLRMT | |
| SCHEMBL24982409 | 0.81 | HIF1A (0.46) | POLRMTSMN1; SMN2ADORA1 | |
| SCHEMBL19101808 | 0.81 | HIF1A (0.46) | POLRMTSMN1; SMN2ADORA1 | |
| SCHEMBL10154369 | 0.81 | HIF1A (0.46) | POLRMTSMN1; SMN2ADORA1 | |
| SCHEMBL25008855 | 0.81 | HIF1A (0.46) | POLRMTSMN1; SMN2ADORA1 | |
| SCHEMBL24982322 | 0.81 | HIF1A (0.46) | POLRMTSMN1; SMN2ADORA1 | |
| SCHEMBL16710417 | 0.81 | HIF1A (0.46) | POLRMTSMN1; SMN2ADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022127914-A1 | NUCLEOSIDE-THIODIPHOSPHATE-HEPTOSE COMPOUNDS FOR TREATING CONDITIONS ASSOCIATED WITH ALPK1 ACTIVITY | PYROTECH (BEIJING) BIOTECHNOLOGY CO., LTD. (CN) | 2022-06-23 | — | — | WO | disclosed |