Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 6/20 | 0.53 |
| ▸ | MAOB | P27338 | 6/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | PDE2A | O00408 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10154064 | 0.85 | APP (0.56) | APPMAOBNPC1RAB9APOLB | |
| SCHEMBL31402943 | 0.85 | APP (0.51) | APPMAOBNPC1RAB9APOLB | |
| SCHEMBL6833539 | 0.84 | APP (0.50) | APPMAOBNPC1RAB9APOLB | |
| SCHEMBL6833613 | 0.84 | MAOB (0.53) | APPMAOBNPC1RAB9APOLB | |
| SCHEMBL189829 | 0.84 | MAOB (0.53) | APPMAOBNPC1RAB9APOLB | |
| SCHEMBL10154073 | 0.81 | APP (0.47) | APPMAOBNPC1RAB9APOLB | |
| SCHEMBL4538153 | 0.81 | MAOB (0.67) | APPMAOB | |
| SCHEMBL27996147 | 0.81 | APP (0.58) | APPMAOBNPC1RAB9APOLB | |
| SCHEMBL17651874 | 0.80 | ENPP2 (0.47) | APPMAOBNPC1RAB9APOLB | |
| SCHEMBL12637245 | 0.79 | APP (0.59) | APPMAOBNPC1RAB9APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120041203-A1 | METAL COMPLEX HAVING AROMATIC RING LIGAND CONTAINING NITROGEN ATOM | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-02-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120041203-A1 | METAL COMPLEX HAVING AROMATIC RING LIGAND CONTAINING NITROGEN ATOM | MICA, CD4, CLTC | APP 2040/4885MAOB 2869/4885NPC1 2642/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.