Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 6/20 | 0.47 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 4/20 | 0.46 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.44 |
| ▸ | CSF1R | P07333 | 1/20 | 0.44 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.44 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.43 |
| ▸ | PDGFRA | P16234 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | PDE5A | O76074 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10154064 | 0.89 | APP (0.56) | APPMAOBNPC1RAB9APOLB | |
| SCHEMBL12637245 | 0.84 | APP (0.59) | APPMAOBNPC1RAB9APOLB | |
| SCHEMBL10154065 | 0.81 | APP (0.53) | APPMAOBNPC1RAB9APOLB | |
| SCHEMBL28366776 | 0.81 | APP (0.65) | APPMAOBNPC1RAB9APOLB | |
| SCHEMBL22305118 | 0.75 | NOS3 (0.50) | MAOBSMN1; SMN2 | |
| SCHEMBL14547341 | 0.74 | CYP17A1 (0.71) | CYP17A1MAOBKDM4EUSP2NPC1 | |
| SCHEMBL4858769 | 0.74 | PLK1 (0.48) | APPCYP17A1MAOBSLC2A1SMN1; SMN2 | |
| SCHEMBL19708786 | 0.73 | CYP17A1 (0.50) | CYP17A1KDM4EUSP2NPC1PDE5A | |
| SCHEMBL791922 | 0.73 | MAOB (0.72) | APPMAOBSLC2A1NPC1RAB9A | |
| SCHEMBL3926741 | 0.73 | MAOB (0.44) | APPMAOBCSF1RKDM4ESLC2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120041203-A1 | METAL COMPLEX HAVING AROMATIC RING LIGAND CONTAINING NITROGEN ATOM | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-02-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120041203-A1 | METAL COMPLEX HAVING AROMATIC RING LIGAND CONTAINING NITROGEN ATOM | MICA, CD4, CLTC | APP 2040/4885CYP17A1 2484/4885MAOB 2869/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.