Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACVR1 | Q04771 | 4/20 | 0.49 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.44 |
| ▸ | KDR | P35968 | 1/20 | 0.44 |
| ▸ | AURKA | O14965 | 1/20 | 0.43 |
| ▸ | TTK | P33981 | 1/20 | 0.43 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.43 |
| ▸ | INCENP | Q9NQS7 | 1/20 | 0.43 |
| ▸ | KIF11 | P52732 | 2/20 | 0.42 |
| ▸ | CA12 | O43570 | 2/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | CA9 | Q16790 | 2/20 | 0.42 |
| ▸ | AAK1 | Q2M2I8 | 6/20 | 0.42 |
| ▸ | TNKS | O95271 | 1/20 | 0.42 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.42 |
| ▸ | HTR2B | P41595 | 1/20 | 0.42 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28925687 | 0.91 | KDR (0.48) | ACVR1PIK3CAKDRAURKATTK | |
| SCHEMBL25878119 | 0.80 | KDR (0.56) | ACVR1KDRKIF11CA12CA1 | |
| SCHEMBL27430955 | 0.77 | ACVR1 (0.52) | ACVR1PIK3CAAURKATTKAURKB | |
| SCHEMBL18327517 | 0.77 | PIK3CA (0.51) | ACVR1PIK3CAAURKATTKAURKB | |
| SCHEMBL24601024 | 0.76 | GRM4 (0.50) | ACVR1PIK3CAKDRAURKBKIF11 | |
| SCHEMBL12074333 | 0.76 | PIK3CA (0.65) | ACVR1PIK3CAKDRAURKATTK | |
| SCHEMBL31222481 | 0.75 | TGFBR1 (0.52) | ACVR1PIK3CAKIF11AAK1TNKS | |
| SCHEMBL18327314 | 0.75 | PIK3CA (0.49) | ACVR1PIK3CAAURKATTKAURKB | |
| SCHEMBL28293866 | 0.75 | PIK3CA (0.46) | ACVR1PIK3CAKIF11MEN1KMT2A | |
| SCHEMBL19991864 | 0.74 | PIK3CA (0.59) | ACVR1PIK3CAAURKATTKAURKB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120041203-A1 | METAL COMPLEX HAVING AROMATIC RING LIGAND CONTAINING NITROGEN ATOM | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-02-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120041203-A1 | METAL COMPLEX HAVING AROMATIC RING LIGAND CONTAINING NITROGEN ATOM | MICA, CD4, CLTC | ACVR1 4739/4885PIK3CA 3535/4885KDR 2768/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.