Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 6/20 | 0.46 |
| ▸ | HTR1A | P08908 | 2/20 | 0.44 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.44 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.44 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | KIF11 | P52732 | 1/20 | 0.40 |
| ▸ | AKT1 | P31749 | 2/20 | 0.38 |
| ▸ | DGAT1 | O75907 | 2/20 | 0.38 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.38 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28175732 | 0.87 | PIK3CA (0.53) | PIK3CAHTR1AADRA1DADRA1AADRA1B | |
| SCHEMBL28295739 | 0.81 | PIK3CA (0.48) | PIK3CAHTR1AADRA1DADRA1AADRA1B | |
| SCHEMBL28925687 | 0.80 | KDR (0.48) | PIK3CAKDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL28295741 | 0.79 | TLR8 (0.51) | PIK3CAHTR1AADRA1DADRA1AADRA1B | |
| SCHEMBL29287969 | 0.76 | PIK3CA (0.49) | PIK3CAHTR1AADRA1DADRA1AADRA1B | |
| SCHEMBL17833787 | 0.75 | PIK3CA (0.48) | PIK3CAHTR1AADRA1DADRA1AADRA1B | |
| SCHEMBL10154084 | 0.75 | ACVR1 (0.49) | PIK3CAMEN1KMT2AKIF11ACVR1 | |
| SCHEMBL23479555 | 0.74 | HTR1A (0.51) | HTR1AADRA1DADRA1AADRA1BKDM4E | |
| SCHEMBL6347874 | 0.74 | KIF11 (0.47) | ADRA1ATSHRKDM4EALDH1A1LMNA | |
| SCHEMBL25878119 | 0.72 | KDR (0.56) | KDM4EALDH1A1MEN1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109796403-B | Quinoline derivatives and preparation method thereof | 安徽师范大学 | 2021-09-28 | — | — | CN | disclosed |
| CN-109796403-A | Quinoline derivatives and preparation method thereof | 安徽师范大学 | 2019-05-24 | — | — | CN | disclosed |