Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLRMT | O00411 | 1/20 | 0.39 |
| ▸ | DOT1L | Q8TEK3 | 3/20 | 0.36 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.35 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.35 |
| ▸ | ADK | P55263 | 10/20 | 0.34 |
| ▸ | HSPA8 | P11142 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19101901 | 0.83 | POLRMT (0.40) | POLRMTDOT1LADKHSPA8 | |
| SCHEMBL806951 | 0.83 | POLRMT (0.40) | POLRMTDOT1LADKHSPA8 | |
| SCHEMBL16479516 | 0.83 | POLRMT (0.40) | POLRMTDOT1LADKHSPA8 | |
| SCHEMBL10101549 | 0.80 | POLRMT (0.36) | POLRMTDOT1LMAP4K4STING1 | |
| SCHEMBL10101489 | 0.80 | POLRMT (0.36) | POLRMTDOT1LMAP4K4STING1 | |
| SCHEMBL4765244 | 0.79 | POLRMT (0.35) | POLRMTDOT1LMAP4K4 | |
| SCHEMBL4765238 | 0.79 | POLRMT (0.35) | POLRMTDOT1LMAP4K4 | |
| SCHEMBL881562 | 0.76 | POLRMT (0.40) | POLRMTDOT1LADKHSPA8 | |
| SCHEMBL10101548 | 0.76 | POLRMT (0.40) | POLRMTDOT1LMAP4K4STING1HSPA8 | |
| SCHEMBL18481207 | 0.76 | POLRMT (0.39) | POLRMTDOT1LADKHSPA8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012012776-A1 | METHODS AND COMPOUNDS FOR TREATING PARAMYXOVIRIDAE VIRUS INFECTIONS | GILEAD SCIENCES, INC. (US) | 2012-01-26 | — | — | WO | disclosed |