Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLRMT | O00411 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.38 |
| ▸ | PDE2A | O00408 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.38 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.36 |
| ▸ | DOT1L | Q8TEK3 | 3/20 | 0.35 |
| ▸ | GAPDH | P04406 | 2/20 | 0.35 |
| ▸ | DPP4 | P27487 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | SLC28A1 | O00337 | 1/20 | 0.35 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.35 |
| ▸ | SLC28A2 | O43868 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.35 |
| ▸ | STAT6 | P42226 | 1/20 | 0.35 |
| ▸ | PI4KA | P42356 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19101901 | 0.92 | POLRMT (0.40) | POLRMTADORA3ADORA2AADORA1PDE2A | |
| SCHEMBL16479516 | 0.92 | POLRMT (0.40) | POLRMTADORA3ADORA2AADORA1PDE2A | |
| SCHEMBL806951 | 0.92 | POLRMT (0.40) | POLRMTADORA3ADORA2AADORA1PDE2A | |
| SCHEMBL19101808 | 0.86 | HIF1A (0.46) | POLRMTADORA3ADORA2AADORA1HIF1A | |
| SCHEMBL10154369 | 0.86 | HIF1A (0.46) | POLRMTADORA3ADORA2AADORA1HIF1A | |
| SCHEMBL24982409 | 0.86 | HIF1A (0.46) | POLRMTADORA3ADORA2AADORA1HIF1A | |
| SCHEMBL16710417 | 0.86 | HIF1A (0.46) | POLRMTADORA3ADORA2AADORA1HIF1A | |
| SCHEMBL25008855 | 0.86 | HIF1A (0.46) | POLRMTADORA3ADORA2AADORA1HIF1A | |
| SCHEMBL24982322 | 0.86 | HIF1A (0.46) | POLRMTADORA3ADORA2AADORA1HIF1A | |
| SCHEMBL881562 | 0.83 | POLRMT (0.40) | POLRMTADORA3ADORA2AADORA1HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170037078-A1 | 2' -DISUBSTITUTED NUCLEOSIDE ANALOGS FOR TREATMENT OF THE FLAVIVIRIDAE FAMILY OF VIRUSES AND CANCER | COCRYSTAL PHARMA, INC. (US) | 2017-02-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170037078-A1 | 2' -DISUBSTITUTED NUCLEOSIDE ANALOGS FOR TREATMENT OF THE FLAVIVIRIDAE FAMILY OF VIRUSES AND CANCER | HAVCR2, HCCS, NAMPT | POLRMT 962/4885ADORA3 330/4885ADORA2A 90/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.