Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 2/20 | 0.67 |
| ▸ | HTR2C | P28335 | 2/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.65 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.65 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.65 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.65 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.60 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.60 |
| ▸ | CA1 | P00915 | 3/20 | 0.56 |
| ▸ | CA2 | P00918 | 3/20 | 0.56 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.54 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.54 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.54 |
| ▸ | HTR5A | P47898 | 2/20 | 0.50 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.50 |
| ▸ | HTR1A | P08908 | 1/20 | 0.50 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.50 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.50 |
| ▸ | DRD2 | P14416 | 1/20 | 0.50 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3927394 | 0.96 | HTR2A (0.67) | HTR2AHTR2CKDM4EHSD17B10ALOX15 | |
| SCHEMBL30223611 | 0.96 | HTR2A (0.67) | HTR2AHTR2CKDM4EHSD17B10ALOX15 | |
| SCHEMBL15307679 | 0.94 | HTR2A (0.65) | HTR2AHTR2CKDM4EHSD17B10ALOX15 | |
| SCHEMBL8791910 | 0.90 | HTR2A (0.56) | HTR2AHTR2CKDM4EHSD17B10ALOX15 | |
| SCHEMBL10309072 | 0.86 | KDM4E (0.64) | HTR2AHTR2CKDM4EHSD17B10ALOX15 | |
| SCHEMBL21311802 | 0.84 | HTR2A (0.53) | HTR2AHTR2CKDM4EHSD17B10ALOX15 | |
| SCHEMBL11818855 | 0.83 | CYP1A2 (0.63) | HTR2AHTR2CKDM4EHSD17B10ALOX15 | |
| SCHEMBL11823048 | 0.82 | CYP1A2 (0.61) | HTR2AHTR2CKDM4EHSD17B10ALOX15 | |
| SCHEMBL12950763 | 0.81 | CYP1A2 (0.65) | HTR2AHTR2CKDM4EHSD17B10ALOX15 | |
| Pnu-22394 SCHEMBL29388570 | 0.80 | HTR2C (1.00) | HTR2AHTR2CKDM4EHSD17B10ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8143399-B2 | Photosensitizer dye | NATIONAL CENTRAL UNIVERSITY (TW) | 2012-03-27 | — | — | US | disclosed |
| US-20090209762-A1 | PHOTOSENSITIZER DYE | NATIONAL CENTRAL UNIVERSITY (TW) | 2009-08-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090209762-A1 | PHOTOSENSITIZER DYE | CRY2, CRY1, PPOX | HTR2A 2953/4885HTR2C 2319/4885KDM4E 3887/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.