Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC7 | O00311 | 2/20 | 0.48 |
| ▸ | PARP1 | P09874 | 1/20 | 0.47 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.46 |
| ▸ | MAPKAPK2 | P49137 | 7/20 | 0.45 |
| ▸ | MAPK9 | P45984 | 4/20 | 0.44 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.44 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.44 |
| ▸ | KDR | P35968 | 1/20 | 0.40 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.40 |
| ▸ | CDK4 | P11802 | 1/20 | 0.39 |
| ▸ | CCND1 | P24385 | 1/20 | 0.39 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.39 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.39 |
| ▸ | BTK | Q06187 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3573147 | 0.79 | MAPKAPK2 (0.71) | CDC7MAPKAPK2MAPK9 | |
| SCHEMBL10155063 | 0.78 | TAAR1 (0.45) | PARP1PKN2PARP10PARP11CYP11B1 | |
| SCHEMBL10154869 | 0.77 | KDR (0.56) | PKN2MAPKAPK2MAPK9KDRCYP11B1 | |
| SCHEMBL10154880 | 0.75 | NISCH (0.47) | CDC7MAPKAPK2MAPK9PARP10PARP11 | |
| SCHEMBL3574892 | 0.73 | CDC7 (0.85) | CDC7MAPKAPK2MAPK9KDRCDK4 | |
| SCHEMBL17847604 | 0.69 | PKN2 (0.56) | CDC7PARP1PKN2MAPKAPK2PARP10 | |
| SCHEMBL17847617 | 0.69 | PKN2 (0.56) | CDC7PARP1PKN2MAPKAPK2PARP10 | |
| SCHEMBL619090 | 0.69 | KDR (0.60) | PARP1KDRCDK4CCND1 | |
| SCHEMBL148203 | 0.67 | TDO2 (0.65) | CYP11B1CYP11B2DYRK1A | |
| SCHEMBL29572015 | 0.67 | TDO2 (0.65) | CYP11B1CYP11B2DYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120040965-A1 | SUBSTITUTED AZEPINO[4,3-B]INDOLES, PHARMACOLOGICAL COMPOSITION AND A METHOD FOR THE PRODUCTION AND USE THEREOF | BORISOVICH FROLOV YEVGENIY (RU) | 2012-02-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120040965-A1 | SUBSTITUTED AZEPINO[4,3-B]INDOLES, PHARMACOLOGICAL COMPOSITION AND A METHOD FOR THE PRODUCTION AND USE THEREOF | ABCG2, HTR3C, AADAC | CDC7 2726/4885PARP1 2055/4885PKN2 2172/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.