SCHEMBL10156252

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL10155145	0.87	HSD17B1 (0.53)	HSD17B1HSD17B2BACE1DYRK1ANPC1
	SCHEMBL10157314	0.84	HSD17B1 (0.59)	HSD17B1HSD17B2BACE1DYRK1A
	SCHEMBL10155026	0.79	BACE1 (0.52)	BACE1
	SCHEMBL29710	0.78	HSD17B1 (1.00)	HSD17B1HSD17B2CYP3A4CYP2D6CYP2C9
	SCHEMBL10157770	0.78	BACE1 (0.63)	BACE1
	SCHEMBL10154834	0.78	BACE1 (0.61)	BACE1
	SCHEMBL10156560	0.77	BACE1 (0.65)	BACE1
	SCHEMBL13333686	0.77	BACE1 (0.54)	BACE1MEN1KMT2A
	SCHEMBL10157519	0.76	SCD (0.65)	BACE1MEN1NPC1RAB9AKMT2A
	SCHEMBL13306619	0.76	BACE1 (0.53)	BACE1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.