SCHEMBL10156034

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL10156575	0.87	LTA4H (0.42)	LTA4HKMT2APKMPPARGP2RX3
	SCHEMBL328299	0.85	PDE4B (0.41)	KMT2APPARGPDE4BSYKNPC1
	SCHEMBL10127132	0.83	SYK (0.38)	KMT2APPARGPDE4BSYKNPC1
	SCHEMBL13070939	0.82	TNF (0.39)	PPARGPDE4BSYKMAPTMAPK8
	SCHEMBL282425	0.80	TNF (0.42)	PPARGNPC1RAB9AMAPTL3MBTL1
	SCHEMBL10157923	0.80	KIT (0.38)	SYKMAPK8
	SCHEMBL10127247	0.79	KMT2A (0.41)	KMT2APPARG
	SCHEMBL283672	0.79	EGFR (0.45)	KMT2ANPC1RAB9AMEN1HTT
	SCHEMBL10156696	0.77	LTA4H (0.41)	LTA4HKMT2APKMP2RX3PDE4B
	SCHEMBL13071122	0.74	NTRK1 (0.47)	KMT2ANPC1RAB9AMEN1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.