SCHEMBL328299

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL10127132	0.85	SYK (0.38)	PDE4BPPARGMEN1KMT2AKDM4E
	SCHEMBL10127142	0.85	PDE4B (0.45)	PDE4BPPARGMEN1KMT2AKDM4E
	SCHEMBL10156711	0.85	PDE4B (0.49)	PDE4BPPARGMEN1KMT2AKDM4E
	SCHEMBL10156034	0.85	LTA4H (0.40)	PDE4BPPARGMEN1KMT2AMAPK8
	SCHEMBL13070939	0.84	TNF (0.39)	PDE4BPPARGLMNAMAPK8MAPT
	SCHEMBL10157923	0.82	KIT (0.38)	MAPK8ZAP70SYKJAK2
	SCHEMBL282425	0.82	TNF (0.42)	PPARGKDM4ELMNAMAPTNPC1
	SCHEMBL10127247	0.81	KMT2A (0.41)	PPARGKMT2ANTRK1JAK2
	SCHEMBL10127167	0.79	NTRK1 (0.38)	PDE4BPPARGMEN1KMT2ATP53
	SCHEMBL10127214	0.78	GSK3A (0.39)	PDE4BPPARGMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.