Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 9/20 | 0.60 |
| ▸ | MAOA | P21397 | 7/20 | 0.60 |
| ▸ | ACHE | P22303 | 4/20 | 0.48 |
| ▸ | BACE1 | P56817 | 1/20 | 0.48 |
| ▸ | BCHE | P06276 | 1/20 | 0.44 |
| ▸ | PYCR1 | P32322 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL621841 | 0.84 | MAOA (0.69) | MAOBMAOAACHEBACE1BCHE | |
| SCHEMBL626003 | 0.81 | MAOB (0.78) | MAOBMAOAACHEBACE1BCHE | |
| SCHEMBL621766 | 0.77 | MAOA (0.69) | MAOBMAOAACHEBACE1BCHE | |
| Hydrochloric Acid SCHEMBL621832 | 0.76 | MAOA (0.68) | MAOBMAOAACHEBACE1BCHE | |
| SCHEMBL620669 | 0.75 | MAOA (1.00) | MAOBMAOAACHEBACE1BCHE | |
| SCHEMBL10156580 | 0.75 | RAD52 (0.40) | KDM4ENPC1ALOX12HTTRAB9A | |
| Hydrochloric Acid SCHEMBL620552 | 0.74 | MAOA (0.98) | MAOBMAOAACHEBACE1BCHE | |
| Hydrochloric Acid SCHEMBL621934 | 0.74 | MAOA (0.98) | MAOBMAOAACHEBACE1BCHE | |
| SCHEMBL15854521 | 0.74 | MAOA (0.51) | MAOBMAOAACHEBACE1BCHE | |
| SCHEMBL623114 | 0.73 | MAOA (0.63) | MAOBMAOAACHEBACE1BCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9034303-B2 | Neuroprotective and neuro-restorative iron chelators and monoamine oxidase inhibitors and uses thereof | ZURAWSKI JR VINCENT R (US) | 2015-05-19 | — | — | US | disclosed |
| US-9034303-B2 | Neuroprotective and neuro-restorative iron chelators and monoamine oxidase inhibitors and uses thereof | ZURAWSKI JR VINCENT R (US) | 2015-05-19 | — | — | US | disclosed |
| US-20140186280-A1 | NEUROPROTECTIVE AND NEURO-RESTORATIVE IRON CHELATORS AND MONOAMINE OXIDASE INHIBITORS AND USES THEREOF | VARINEL INC (US) | 2014-07-03 | — | — | US | disclosed |
| US-20140186280-A1 | NEUROPROTECTIVE AND NEURO-RESTORATIVE IRON CHELATORS AND MONOAMINE OXIDASE INHIBITORS AND USES THEREOF | VARINEL INC (US) | 2014-07-03 | — | — | US | disclosed |
| WO-2012020389-A1 | NEUROPROTECTIVE AND NEURO-RESTORATIVE IRON CHELATORS AND MONOAMINE OXIDASE INHIBITORS AND USES THEREOF | VARINEL INC (US) | 2012-02-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140186280-A1 | NEUROPROTECTIVE AND NEURO-RESTORATIVE IRON CHELATORS AND MONOAMINE OXIDASE INHIBITORS AND USES THEREOF | MAOA, MAOB, FECH | MAOB 2/4885MAOA 1/4885ACHE 24/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.